Clinician Scientist PRogram In Vascular MEdicine: PRIME

血管疾病是全世界死亡率和发病率的主要原因之一。这导致了巨大的保健问题，并产生了负面的社会经济影响。更好地了解血管疾病的病理生理基础，确定新的治疗靶点，并将研究概念转化为临床应用，是治疗和预防血管疾病的重要前提。临床科学家对于新疗法的识别和成功的临床建立具有突出的重要性。然而，在“板凳”和“床边”工作的医生严重短缺。这部分是由于临床医生科学家的临床-科学综合培训没有得到充分的监管。在2018年德国研究基金会（DFG）的招标之后，我们申请为年轻的执业医生建立一个名为“血管医学临床科学家PRrogram（PRIME）”的研究和培训计划。该计划的中心目标是有针对性地促进活跃于血管焦点的年轻医生的临床和科学能力。在3年的时间里，接受专科培训的医疗专业人员有机会灵活使用50%的工作时间作为受保护的研究时间。该计划伴随着结构化课程中的跨学科和个性化培训，以及研究经验丰富的导师的密切监督。该计划促进了实验，转化和临床研究的成功实施，同时确保了作为专家的临床培训没有明显的延迟。该培训计划面向所有专业学科的血管相关研究医生，同时也考虑到较小的专业学科（例如心脏外科，实验室医学），这些学科到目前为止通常很难参与此类计划。总之，我们建立了一个跨学科的，以血管为重点的培训计划，称为“PRIME”，这对研究医生的结构化，科学合理的培训做出了重要贡献。该计划已被纳入慕尼黑临床医生科学家计划（MCSP）的框架。随着LMU医学院的可持续发展理念，我们正在开辟新的职业道路，并确保有才华的医生超越他们的专业资格晋升。因此，PRIME将为血管疾病的研究、治疗和预防做出重要贡献。

Vascular diseases are among the leading causes of mortality and morbidity worldwide. This leads to enormous problems in health care and has negative socio-economic effects. A better understanding of the pathophysiological basis of vascular diseases, the identification of new therapeutic targets and the transfer of research concepts into clinical applications are important prerequisites for the treatment and prevention of vascular diseases. Clinician scientists are of outstanding importance for the identification and successful clinical establishment of new therapies. However, there is a significant shortage of doctors working at both “bench” and “bedside”. This is in part due to the fact that the combined clinical-scientific training of clinician scientists is only inadequately regulated. Following the tender of the German Research Foundation (DFG) in 2018, we applied for the establishment of a research and training program with the title “Clinician Scientist PRrogram In Vascular Medicine (PRIME)” for young licensed doctors. The central goal of the program is the targeted promotion of clinical and scientific competencies of young physicians active with a vascular focus. Over a period of 3 years, medical professionals in specialist training have the opportunity to flexibly use 50% of their working hours as protected research time. The program is accompanied by interdisciplinary and individually adapted training within a structured curriculum as well as close supervision by research-experienced mentors. The program promotes the successful implementation of experimental, translational and clinical research, and at the same time ensures clinical training as a specialist without significant delay. The training program is accessible to vascular-interested researching doctors from all specialist disciplines, and also takes into account smaller specialist disciplines (e.g. cardiac surgery, laboratory medicine), for which participation in such programs has often been difficult up to now. In summary, we established an interdisciplinary, vascular-focused training program termed “PRIME”, which makes an important contribution to the structured, scientifically sound training of researching doctors. The program has been integrated into the framework of the Munich Clinician Scientist Program (MCSP). With the accompanying sustainability concept of the LMU Medical Faculty, we are opening up new career paths and ensure that talented doctors are promoted beyond their specialist qualification. PRIME will therefore make an important contribution to the research, treatment and prevention of vascular diseases.