Advancement of the Functions of Molecular Assemblies Composed of Amphiphilic Molesules

微乳液是一种由两亲性分子组成的分子组合，我们对微乳液的功能进行了研究。得到的结果如下：1。单位分子组装功能：阐述了提高单位分子组装功能的基本内容；(1)表面活性剂分子形态与组装体几何形状之间的理论模型；(2)表面活性剂体系产生球形和圆柱形组装体的行为；(3)客体分子向主体组装体中增溶的特性；(4)非离子表面活性剂体系和非离子和阴离子混合表面活性剂体系中组装体的特性；(5)组装体在制备CdS细颗粒中的作用。表面活性剂/蛋白质系统的功能：阐明了组件中蛋白质溶解的驱动力和客体分子的溶解动力学。在此基础上，我们提出了定制分子组装的方法，用于蛋白质的增溶和不变性蛋白质的选择性分离。这些方法是基于调节蛋白质和表面活性剂之间的静电和亲和相互作用。浓缩组装体系的功能：阐明了由浓缩气溶胶- ot组成的球形组装体系的静态和动态特性，以及浓缩二（2乙基己基）磷酸钠体系的网状微结构。我们还获得了微乳中纳米结构凝固的基本信息。

We performed the studies on advancing the functions of a microemulsion which is a kind of molecular assemblies composed of amphiphilic molecules. The obtained results are as follows.1. Functions of unit molecular assembly : We elucidated the fundamental items for advancing the functions of unit assembly ; (1) theoretical model relating the surfactant molecular form with the geometry of the assembly, (2) the behaviors of the surfactant systems yielding spherical and cylindrical assemblies, (3) the characteristics of the solubilization of guest molecules into the host assemblies, (4) the characteristics of the assemblies in non-ionic surfactant systems and in non-ionic and anionic mixed surfactant systems, and (5) the roles of the assemblies in the preparation of CdS fine particles.2. Functions of surfactant/protein systems : We elucidated the driving force for solubilizing proteins in the assemblies and the solubilization dynamics of guest molecules. Based on these, we proposed the methods of tailoring molecular assemblies for protein solubilization and selective separation of proteins without denaturation of proteins. The methods are based on regulating the electrostatic and affinity interactions between proteins and surfactants.3. Functions of concentrated assembly systems : We elucidated the static and dynamic characteristics both of the spherical assembly system composed of concentrated Aerosol-OT and of the network micro-structures in concentrated sodium bis (2ethylhexyl) phosphate system. We also obtained fundamental information on the solidification of nano-structures in microemulsions.