A Multiscale Modelling Platform for Nanoparticle Inhalation Risk Assessment

该项目旨在探索吸入纳米颗粒及其通过呼吸道粘液和组织细胞渗透所造成的健康风险。接触纳米颗粒有可能造成严重的、甚至可能致命的健康影响。了解纳米颗粒毒理学将使我们能够适当地保护公众的健康和安全。该项目计划考虑人体呼吸道解剖学和生理学，并使用先进的计算机建模和实验技术来评估接触消费产品中迅速增长的纳米材料的健康风险。该项目的预期结果是一种预测工具，可以确定纳米颗粒暴露的风险及其健康后果。

This project aims to explore the health risks caused by nanoparticle inhalation and its penetration through respiratory mucus and tissue cells. Exposure to nanoparticles has the potential to cause serious and possibly fatal health effects. An understanding of nanoparticle toxicology would enable us to appropriately protect the public’s health and safety. The project plans to consider human respiratory anatomy and physiology and use advanced computer modelling and experimental techniques to evaluate the health risk of exposure to the burgeoning number of nanomaterials found in consumer products. The expected outcome of the project is a predictive tool that determines nanoparticle exposure risk and its health consequences.