Drug particle characterisation

药物颗粒表征

• 批准号: LP0561870
• 负责人: Prof Jiyuan Tu
• 金额: $ 10.51万
• 依托单位: RMIT University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2005
• 资助国家: 澳大利亚
• 起止时间: 2005-10-20 至 2008-10-19
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP0561870
• 关键词: Drug; particle; characterisation

The understanding of drug particle characterizations is one of the key issues in the development of novel nasal sprayers for targeted drug delivery. A comprehensive study is proposed for characterising drug formation in sprayers and particle deposition in nasal cavity using the latest experimental and numerical techniques. A computer-aided design technology will be developed to optimise drug delivery systems. The new technology has great potentials leading to therapeutic and economic benefits in developing advanced/innovative drug delivery systems and in evaluating the potential biological effects by the drugs to be introduced through the nose.

对药物颗粒特征的了解是开发新型靶向药物输送鼻喷雾器的关键问题之一。提出了一个全面的研究，采用最新的实验和数值计算技术表征药物形成的喷雾器和颗粒沉积在鼻腔。 将开发一种计算机辅助设计技术，以优化药物输送系统。该新技术在开发先进/创新的药物递送系统和评估通过鼻引入的药物的潜在生物效应方面具有巨大的潜力，从而产生治疗和经济效益。