Synthesis and Characterisation of Encoded Hybrid Polymer/Gold Nanoparticles for Application in Bioassays

生物测定是体外诊断和生物医学研究的基石。该提案将通过针对对其未来发展至关重要的新兴技术，为这些领域做出重大贡献。在这个项目中描述的混合纳米粒子有可能取代目前用于生物测定的传统检测策略。在这样做的过程中，它们应该比传统的检测策略具有显著的优势。这些优点包括增加样品吞吐量和生物样品的保存，这使得加速患者诊断和药物发现成为可能。

Bioassays are the cornerstone of in vitro diagnostic and biomedical research. This proposal will significantly contribute to these areas, by targeting an emerging technology that is crucial for their future development. The hybrid nanoparticles described in this project have the potential to replace conventional detection strategies that are currently used for bioassays. In doing so, they should provide significant advantages over conventional detection strategies. These advantages include increased sample throughput and conservation of biological samples, which makes possible the acceleration of patient diagnosis and drug discovery.