Abnormal connectivity in schizophrenia revealed by multi-modal MRI

采用结构MRI和弥散张量成像（DTI）对精神分裂症患者的异常连通性进行了研究。在使用结构MRI对灰质进行分析时，揭示了健康人的皮层厚度和年龄与精神分裂症之间的关系。在白质的DTI分析中，正常的脑白质不对称性在精神分裂症中被减少或夸大。这种异常的不对称也被揭示为精神分裂症某些症状的神经关联。

Abnormal connectivity in schizophrenia was investigated by means of the structural MRI and diffusion tensor imaging (DTI). In the analysis of gray matter using structural MRI, the association between cortical thickness and age in healthy people and schizophrenia was revealed. In the DTI analysis for white matter, normal cerebral white matter asymmetry was revealed to be reduced or exaggerated in schizophrenia. This abnormal asymmetry was also revealed to be the neural correlate of certain symptoms of schizophrenia.