Oxyenamides and Oxyencarbamates as novel building blocks for the rapid construction of molecular complexity

高效合成含有多个立体中心的复杂分子仍然是有机化学中的一个重大挑战。在这个项目的过程中，我们建立了2-氧酰胺和相应的2-氧氨基甲酸酯作为立体选择性合成结构复杂分子的新工具。我们的目标是模块化的过程，以控制尽可能多的立体异构体的一个给定的分子，从一组简单的共同构建模块开始。最后，我们想要证明我们的方法在选定目标的合成中的适用性。

The efficient synthesis of complex molecules containing multiple stereocenters still represents a major challenge in organic chemistry. In the course of this project we establish 2-oxyenamides and the corresponding 2-oxyencarbamates as novel tools for the stereoselective synthesis of structurally complex molecules. Our goals are modular processes for a controlled construction of as many stereoisomers as possible of a given molecule starting from a simple set of common building blocks. Finally we want to demonstrate the applicability of our methods in the synthesis of selected targets.