Physical Responses in Chronic Pain Patients and Modifying Factors of Pain

1.通过适当的日语翻译，本研究证实了麦吉尔疼痛问卷(MPQ)(Melzack，1975)中的78个条目是有效的疼痛术语。其他没有出现在MPQ中的项目被找到。结论1.了解疼痛，重要的是要考虑疼痛强度的时间序列模式、物理环境，如天气、患者的社会背景和他们的心理状态。慢性疼痛患者的痛阈值高于健康人。部分慢性疼痛患者血清中促肾上腺皮质激素、β-内啡肽含量较无疼痛患者明显增多。这说明慢性疼痛患者处于应激状态。提示炎症区域的皮肤血流量可作为慢性风湿性关节炎患者的疼痛指标。研究发现，在局麻下手术中，患者有时会出现过度耐受的疼痛。说明护理止痛剂护理，如舒适的香水和冷敷，在止痛方面与药物一样有效。本研究的最终目的是“更正确地理解疼痛”，“开发超越MPQ的综合疼痛评估工具”。因此，作者正在继续对各种慢性疼痛患者进行研究。然后，我们计划研究慢性疼痛与受试者的行为或心理状态的相互关系，以及疼痛与人体生理变化的相互关系。

1. This study confirmed that seventy-eight items in the McGill Pain Questionnaire (MPQ) (Melzack, 1975) are valid as pain terms by suitable Japanese translation. The other items that do not appear in MPQ were found. Understanding pain, it is important to consider time series pattern of pain intensity, physical environments, such as weather, social background of the patients and their psychological status.2. The pain thresholds of the chronic pain patients were higher than those of the healthy subjects. In some chronic pain patients, ACTH, β-endorphin can be observed in blood serum more than before they had had no pain. This indicates that chronic pain patients are in the stressful conditions.3. It is suggested that cutaneous blood flow volume at the inflammation area can be a pain indicator in chronic rheumatic arthritis patients4. It is found that patients sometimes experienced over-tolerate pain during the operations under local anesthesia.5. It is clarified that nursing analgesic cares, such as comfortable perfume and cold compress, are as effective as drugs in pain management. Moreover, combined analgesic cares are much more effective than a single care implementation.The ultimate aim of this research is "understanding pain more correctly" , and "developing comprehensive pain assessment tool that surpasses MPQ" . Therefore, the authors are continuing to study in various chronic pain patients. Then we plan to investigate interrelationship between the chronic pain and the behavior or the mental status of the subjects, and also between the pain and the physiological change in human body.