Coreceptors of abscisic acid and their SnRK2 protein kinase targets as regulators of plant metabolism and growth

植物整合环境和内源信号，以优化生长和适应。植物激素脱落酸(ABA)是植物协调萌发、蒸腾和生长以适应环境的关键因子。ABA是水分胁迫下诱导的主要非生物胁迫信号。在水分充足的条件下，ABA还在微调生长和控制碳代谢方面发挥关键作用。这两个调控过程只在分子水平上得到了初步的理解。该项目旨在阐明ABA信号调节叶片起始和碳代谢的分子机制。根据初步结果，已经提出了工作假说，即特定的ABA辅助受体及其靶向的SnRK2s蛋白激酶是这些调控过程的关键角色。该项目的目标将分三个工作包进行，旨在确定负责叶片启动和控制碳代谢的ABA辅助受体和SnRK2蛋白激酶，分析ABA辅助受体对SnRK2的调节，以及确定下游作用靶标。

Plants integrate environmental and endogenous signals to optimize growth and fitness. The phytohormone abscisic acid (ABA) is a key player that allows plants to coordinate germination, transpiration, and growth in response to the environmental setting. ABA is the prime abiotic stress signal induced under water deficit. Under well-watered conditions, ABA also fulfills crucial roles in fine-tuning growth and controlling carbon metabolism. Both these regulatory processes are only rudimentarily understood on a molecular level. The project aims to elucidate the molecular mechanisms of ABA signaling for regulating leaf initiation and carbon metabolism. Based on preliminary results the working hypothesis has been developed that specific ABA coreceptors and their targeted SnRK2s protein kinases are key players of these regulatory processes. The project goal will be pursued in three work packages addressing the objective of defining the responsible ABA coreceptors and SnRK2 protein kinases for leaf initiation and controlling carbon metabolism, analyzing the SnRK2 regulation by ABA coreceptors, and identifying downstream acting targets.