Root-end sealing of adhesive resin

在根管内存在细菌的情况下，根尖周手术后逆行充填有必要防止细菌从根管渗入根尖周围组织。第一项研究的目的是评价4-META/MMA-TBB树脂与牙骨质的粘附性。牙骨质的微拉伸粘结强度和渗漏水平与牙本质几乎相同，牙本质和牙骨质之间的粘结耐久性没有显著差异。第二项研究的目的是评价4-META/MMA-TBB树脂根管封闭术后染料渗漏的情况。4-META/MMA-TBB树脂根端封闭剂的长期封闭性好于增强氧化锌丁香酚粘固剂或高铜银汞合金逆行根管充填。第三项研究的目的是评价在不同条件下固化的4-META/MMA-TBB树脂表面的炎症情况。结果表明，暴露在空气中固化的树脂周围的炎性结缔组织面积大于用空气阻隔条固化并在固化后抛光的面积。因此，固化条件对4-META/MMA-TBB树脂的生物相容性有影响。第四项研究的目的是评估根端封闭后的愈合情况，并与传统的根管逆行充填技术进行比较。4-META/MMA-TBB树脂根尖封闭后的骨愈合优于增强氧化锌丁香酚粘固剂逆行根管充填，并观察了高铜银汞合金逆行根管充填后的骨缺损。第五项研究的目的是评价根尖切除术后用4-META/MMA-TBB树脂根尖封闭后的愈合情况。骨再生明显，可见牙周韧带正常间隙。结论：4-META/MMA-TBB根管封闭剂在根尖周手术中具有较好的应用前景。

In the case of the presence of bacteria in the root canals, it is necessary that retrograde filling following periapical surgery prevent the leakage of bacteria from root canals into periapical tissues. The purpose of first study was to evaluate the adhesion of 4-META/MMA-TBB resin to cementum. The micro-tensile bond strength and the leakage levels obtained for the cementum were almost equal to those for the dentin, and no significant difference in durability of adhesion was recognized between dentin and cementum. The purpose of second study was to evaluate that the dye leakage from root canal after root-end sealing using 4-META/MMA-TBB resin. Root-end sealing using 4-META/MMA-TBB resin performed better sealing for long term than retrograde root filling by reinforced zinc oxide-eugenol cement or high copper amalgam alloy. The purpose of third study was to evaluate inflammation at the surfaces of 4-META/MMA-TBB resin cured under various conditions. The results showed that the area of inflammatory connective tissue around the resin cured by exposure to air was larger than that cured by using a strip for air barrier and polished after curing. Thus, the curing conditions of 4-META/MMA-TBB resin influenced biocompatibility. The purpose of fourth study was to evaluate the healing after root-end sealing compared with conventional technique of retrograde root filling following intentional replantation. The bone healing after root-end sealing using 4-META/MMA-TBB resin was better than retrograde root filling using reinforced zinc oxide-eugenol cement, and the bone defect after retrograde using high copper amalgam alloy was observed. The purpose of fifth study was to evaluate the healing after root-end sealing using 4-META/MMA-TBB resin following apicoectomy. The bone regeneration was remarkable and the normal space of the periodontal ligament was observed. It could be concluded that root-end sealing using 4-META/MMA-TBB rein has a better potential in periapical surgery.