Effects of Food Restriction during Puberty and Pregnant Period on the Maternal Body and Growth of Progeny

研究了青春期和青春期妊娠期大鼠限食对母体和子代生长的影响。7周龄雌性大鼠分为三组：一组(CC组)随机喂养(10%酪蛋白+10%大豆蛋白饲料)，另两组限食组(CR组)或青春期妊娠期(RR组)喂养比CC组少30%。限食和随意喂养的动物是成对喂养的。各组孕鼠均维持妊娠并进行正常分娩和哺乳。与CC组相比，青春期限食对RC组仔猪和断奶仔猪的母体和仔猪生长没有显著影响。与CC组相比，青春期-妊娠期限食降低了RR组的母体增重和腹脂重量。RR组新生仔鼠体重和脏器重量显著低于CC组。出生后3周，与CC组相比，RR组断奶仔鼠生长发育迟缓。结果表明，青春期-妊娠期限食对母体和子代生长发育有明显影响。

The effects of food restriction in rats through puberty or puberty- pregnancy period on the maternal body and growth of the progeny were studied. We prepared three groups of 7 weeks old female rats : one group (CC group) fed ad libitum (10% casein and 10% soy protein diet) and two food-restricted groups fed 30% less than the CC group through puberty (CR group) or puberty-pregnancy period (RR group). The food-restricted and ad libitum- fed animals were pair-fed. All groups of pregnant rats maintained pregnancy and performed normal delivery and lactation. Food restriction through puberty did not affect remarkably on the maternal body and growth of the newborn pups and weaning progeny of RC group in comparison with the CC group. Food restriction through puberty-pregnancy period reduced the maternal body weight gain and the abdominal fat weight of the RR group when compared with the CC group. The body weight and organ weight of newborn pups in the RR group were significantly lower than those of the CC group. At 3 weeks after birth retarded growth was observed in the weaning progeny of the RR group in comparison with the CC group. We conclude that the food restriction through puberty-pregnant period markedly affected the maternal body and growth of the progeny.