Rotavirus infection in children and adults : how they related to each other.

大约10%的成人腹泻是由轮状病毒感染引起的，但在儿童中传播的轮状病毒与在成人中传播的轮状病毒之间的关系尚不清楚。在本研究中，从同一地理位置的儿童和成人收集轮状病毒标本，以确定两者之间的关系。在1999年12月至2000年3月的4个月期间，84例成年腹泻患者的标本中有17例轮状病毒检测呈阳性。共有4株G9和4株G2。发现G9 VP7不属于先前已知的三个谱系中的任何一个。因此，它可以代表一个新的血统。在2000年至2004年的4年期间，从儿童和成人腹泻患者中共收集了1,081份粪便标本。对这些标本进行聚丙烯酰胺凝胶电泳，发现成人和儿童均为轮状病毒腹泻的高发季节，但鉴定的高发年份不同，不一定是典型的11月至3月。儿童的菌株多样性大于成人，这表明形成这种流行病的是儿童病例。流行病的规模似乎受到儿童流行病的严重程度的影响。

Approximately 10% of adult diarrhea was caused by rotavirus infection, but the relationships between rotaviruses circulating among children and those circulating among adults remain unclear. In this study, Rotavirus specimens were collected from both children and adults in the same geographic location in order to determine the relationships between them. During the 4 month period between December 1999 and March 2000, 17 of 84 specimens from adult patients with diarrhea were tested positive for rotavirus. There were 4 G9 and 4 G2 strains. The G9 VP7 was found not to belong to any of the previously known three lineages. It therefore can represent a new lineage. During the 4 year period between 2000 and 2004, a total of 1,081 stool specimens were collected from both children and adult patients with diarrhea. When these specimens were subjected to polyacrylamide gel electrophoresis, it was found that the peak season of rotavirus diarrhea coincides with both adults and children but the peak incidence of identification was different from one year to another, and not necessarily classical November to March. The diversity of strains was larger in children than in adults, suggesting that what formed the epidemic were cases in children. The size of epidemic appears to effected by the magnitude of the epidemic in children.