DEVELOPMENT OF NON-RI SENTINEL NAVIGATION SURGERY FOR LUNG CANCER

我们测试了非ri导航手术治疗肺癌的可行性。在本研究中。我们使用吲哚菁绿（icg）作为示踪剂。由于icg在红外波段显示吸收光谱，因此通过红外相机（内窥镜）系统进行观察。开胸后，直接在肿瘤周围肺组织内注射icg 25mg / 5ml，不经手术观察。已登记的6例中。行常规肺叶切除及全身淋巴结清扫。未发现淋巴结转移，未发生不良反应。通过红外摄像机观察清扫淋巴结，6例患者均在多站清晰地观察到他汀类药物的作用。这显示了icg作为肺癌手术示踪剂的实用性。然而，术中红外内窥镜观察，我们仅发现1例hirnal淋巴结染色。我们认为通过结缔组织或胸膜的穿透力仍然不足。此外。淋巴流量的变化可能与个体视觉有关。现在我们正在研究门和纵隔的淋巴结，以了解肺和其他器官，门和纵隔之间的区别，并通过单独的视觉。

WE TESTED THE FEASIBILITY OF NON-RI NAVIGATION SURGERY FOR LUNG CANCER. IN THE PRESENT SUTDY. WE USED INDOCYANINE GREEN (ICG) AS A TRACER. OBSERVATION WAS PERFORMED THROUGH INFRAED CAMERA (ENDOSCOPE) SYSTEM BECAUSE ICG SHOWS ABSOUPTION SPECTRUM IN INFARED BAND. AFTER THORACOTOMY, 25MG/5ML OF ICG WAS INJECTED INTO LUNG TISSUE SURROUNDING TUMOR DIRECTLY AND OBSERVATION WAS PERFORMED WITHOUT OPERATION PROSEDURE. IN SIX CASES REGISTERED. USUAL LOBECTOMY AND SYSTEMIC NODAL DISSECTION WAS PERFORMED. NO NODAL METASTASIS WAS FOUND AND NO ADVERSE EFFECT OF ICG ADMINISTRATION WAS OCCURRED. BY OBSERVING DESSECTED LYMPH NODES THROUGH INFRARE CAMERA, ICG STATINING WAS CLEARLY OBSERVED AT MULTI-STATION IN ALL OF SIX CASES. THAT SHOWS THE USEFULNESS OF ICG FOR A TRACER OF LUNG CANCER OPERATION.HOWEVER, BY INTRAOPERATIVE OBSERVATION THROUGH INFRAED ENDOSCOPE, WE COULD DETECT HIRAL NODE STAINING ONLY IN ONE CASE. WE SUGGEST THAT THE PENETRATION POWER THROUGH CONNECTIVE TISSUE OR PLEURA IS STILL INSUFFICIENT. IN ADDITION. VARIATION OF LYMPHATIC FLOW BY INDIVISUALS MIGHT BE INVOLVED. NOW WE ARE INVESTIGATING THE LYMPH NODES OF HILUM AND MEDIASTINUM TO KNOW THE DIFFERENCE BETWEEN LUNG AND THE OTHER ORGANS, BETWEEN HILUM AND MEDIASTINUM, AND BY INDIVISUALS.