Development of Novel "Nonamphiphilic" Polymeric Micelles

我们发现了完全由亲溶剂链段组成的“非两亲性”聚合物的新型胶束形成，并利用这种胶束形成开发了新的聚合物材料。我们制备了侧链带有给电子基的非两亲性嵌段共聚物和无规共聚物。共聚物本身没有自组装现象。光散射研究表明，在添加剂的存在下，共聚物形成了纳米尺度的球形胶束，添加剂与共聚物的侧基相互作用或促进了盐的形成。胶束的大小和聚集数取决于聚合物的相对分子质量、添加剂的官能度和结构，这表明胶束的大小和聚集数可以由这些因素控制。对胶束形成的热力学和动力学进行了探讨，测定了胶束形成的焓和熵。此外，我们还通过官能团嵌段共聚物胶束的形成成功地制备了功能纳米粒子。嵌段共聚物与染料分子和紫外线吸收剂的胶束作用产生了高度光稳定性的纳米染料。

We found novel micelle formation of "nonamphiphilic" polymers consisting entirely of solvophilic segments and developed new polymeric materials using the micelle formation. We prepared nonamphiphilic block copolymers and random copolymers having electron-donating groups at the side chains. The copolymers showed no self-assembly by themselves. The light scattering studies demonstrated that the copolymers formed spherical micelles with a nanoscale in the presence of additives which have an interaction or promote salt formation with the side groups of the copolymers. The size and aggregation numbers of the micelles were dependent on the molecular weight of the polymers, the functionality and structure of the additives, indicating that the size and aggregation numbers of the micelles could be controlled by these factors. We also explored the thermodynamics and kinetics of the micellization and determined the enthalpy and entropy of the micelle formation. Furthermore, we succeeded in preparing functional nanoparticles through the micelle formation of block copolymers with functional groups. The micellization of block copolymers with dye molecules and UV absorbents produced highly light-stable nanodyes.