A Research Project for Diagnosis, Treatment and Pathophysiology of Small Intestinal Diseases Using Double-Balloon Endoscopy.

截至2006年3月底，我们已经使用双气囊内镜进行了530多例肠镜检查。根据这些经验，我们建立了双气囊内窥镜的插入方法。并建立了小肠内的治疗方法，如止血、息肉切除、球囊扩张等，支架置入和取出异物。我们还进行了一项多中心试验，与独协大学合作，开展了气囊内镜和胶囊内镜，以建立小肠疾病的标准入路策略。我们还积极开展了小肠段内镜入路，具有手术改变的解剖结构的管道，这在标准内窥镜检查中是困难的，例如Billroth II或Roux-en-Y重建的输入支使用双气囊内窥镜。我们建立了双气囊内镜下胆道镜治疗这类患者的方法，并进行了多中心的研究。 ...更多信息 在一个由自治医科大学、日本医科大学、名古屋大学、京都大学、广岛大学、九州大学和福冈大学组成的工作组中，对小肠疾病的研究进行了试验。该工作组由2003年成立的小肠内镜学会的核心成员组成，并致力于双气囊内镜的国际教育和推广。因此，双气囊内窥镜目前在世界上超过33个国家使用。欧洲、美洲和大洋洲已有许多出版物报告了双气囊内窥镜的有效性和安全性。双气囊小肠镜已成为国际上公认的小肠镜检查新标准。我们组织了第一届国际双气囊内窥镜研讨会，将于2006年8月在东京举行，以分享经验，标准化技术，提高我们对小肠疾病的认识。国际委员会由来自日本、美国、加拿大、德国、荷兰、中国和韩国的代表组成。具体来说，我们部门的一名研究人员被派往我们大学的微生物学系进行肠道细菌植物群的研究。我们的第一个目标是阐明正常的细菌植物群的人小肠。少

We have experienced more than 530 cases of enteroscopy using double-balloon endoscopy by the end of March 2006. From these experiences, we have established the insertion method of double-balloon endoscopy. We also established the therapeutic method in the small intestine, such as hemostasis, polypectomy, balloon dilation, stent placement and retrieval of foreign bodies.We also performed a multi-center trial of a comparison between double-balloon endoscopy and capsule endoscopy in cooperation with Dokkyo University to establish the standard approaching strategy for the small intestinal diseases.We also actively performed endoscopic approaches to a segment of intestinal tracts with surgically altered anatomy, which had been difficult with standard endoscopy, such as an afferent limb of Billroth II or Roux-en-Y reconstruction using double-balloon endoscopy. We established endoscopic billiary treatments with double-balloon endoscopy for such kind of patients.We also performed multi-center … More trials of research on small intestinal diseases in a working group which is composed of Jichi Medical University, Nippon Medical University, Nagoya University, Kyoto University, Hiroshima University, Kyushu University and Fukuoka University. The working group was organized with the core members of the society for the study of small intestinal endoscopy which was established in 2003.We also worked for international education and spreading of double-balloon endoscopy. As a result, double-balloon endoscopy is currently used in more than 33 countries in the world. There are already many publications from Europe, America and Oceania which report usefulness and safety of double-balloon endoscopy. Double-balloon endoscopy has been accepted as a new standard of enteroscopy in an international level. We have organized the 1st International Workshop on Double-Balloon Endoscopy which will be held at Tokyo in August of 2006 to share the experience, standardize the technique and improve our knowledge on small intestinal diseases. International committee of the workshop is composed of delegates from Japan, America, Canada, Germany, Netherlands, China and Korea.Basic research on the small intestine using double-balloon endoscopy is also ongoing. Specifically, a researcher of our division is sent to the department of microbiology in our university for the study of the intestinal bacterial flora. Our first aim is to elucidate the normal bacterial flora of the human small intestine. Less