Establishment of predictive Assay for radiosensity of tumors

在恶性肿瘤的放射治疗中，如果能在治疗开始前就能估计肿瘤的放射敏感性，加速照射、超分割照射等适宜的照射分次就能更合理地选择，适应性强，治疗效果的改善就有希望。肿瘤的放射反应可以无创性地进行评价，本研究关注的是放射性核素19F。19F在体图像可用于细胞功能的评价。本文研究了19F线圈自旋回波、梯度回波等脉冲序列的优化。在任何顺序中，19F的信号强度都非常低，没有导致优化。在任何顺序下，信号强度都非常低，没有导致顺序的优化。该研究无法发布。

On the occasion of radiation treatment of the malignant tumor, if radiosensitivity of the neoplasm can be estimated before the treatment begining, the fractionation-of-irradiation which the accelerated irradiation, the hyperfractionate irradiation and so on are appropriate to become able to be more rational chosen, being adaptable and the improvement of the treatment results can look forward to it. If the MRI can evaluate radiosensitivity of the neoplasm, the radiation-response of the neoplasm can be esimated with non-invasiveness.In this research, it paid attention to fluoric nucleus (19F). The evaluation of the cell function will become possible with 19F in vivo imageIt examined the optimization of the pulse sequences such as the spin echo, the gradient echo with 19F coil. In any order, the signal-strength of 19F was low extremely and didn't result in the optimization. In any order, the signal-strength was low extremely and didn't result in the optimization of the order. The research could not be released.