Chiral Organosilanes With Si–O Functions – From Selective Molecular Transformations to Chiral Materials

这里描述的研究项目旨在从工业上使用的硅烷醇、硅氧烷或有机硅化合物类别中获得新的有价值的硅立体物质，并扩大对取代反应的理解。手性可及分子将被用作硅立体探针，以获得对硅中心发生的基本过程的新见解，包括水解和缩合反应。手性反应Si-O和Si-N体系将被引入到复杂手性结构或材料的构建中。同位素标记与手性结合是硅化学中一种新的分析方法。在这一研究领域的相应的初步研究已经揭示了意想不到的，否则看不见的选择性分子转化。其目的是通过增加对硅上分子反应的机械理解来拓宽选择性合成不同Si-O-官能化材料的光谱。

The research project described here is intended to make new valuable silicon-stereogenic substances from the industrially used compound classes of silanols, siloxanes or silicones accessible and to expand the understanding of substitution reactions. The chiral accessible molecules will be used as Si-stereogenic probes to gain new insights into fundamental processes taking place at the silicon center, including hydrolysis and condensation reactions. Chiral reactive Si–O and Si–N systems will be incorporated into the construction of complex chiral structures or materials based on these mechanistic understandings. The combination of isotope labelling and chirality is a new analytical approach in silicon chemistry. Corresponding initial studies in this research field already revealed unexpected, otherwise invisible selective molecular transformations. The aim is to broaden the spectrum for selective synthesis of the diverse Si–O-functionalized materials through increased mechanistic understanding of molecular reactions on silicon.