Exploration of the innovation patterns in emerging, highly convergent life sciences domains

2017财年，我完成了汇聚科学研究的全球地图绘制，其中包括处理所有科学领域的150万份出版物和2.4万个集群。在这张地图上，我选择了三个高度融合的生命科学领域的案例来考察它们的创新模式：(A)对影响新兴iPS细胞疗法演变的因素的研究，(B)对下一代癌症免疫疗法的演变和协作模式的研究，以及(C)对日本WPI研究中心的融合的评估。对于这些病例，我们使用了一种混合方法，包括科学、技术和临床数据。为了进行这项研究，建立了不同的国内和国际合作伙伴关系。这项研究的主要成果是两份手稿，目前正在审查中，一旦获得接受，将被添加到这笔赠款中。2017财年，我转行到京都大学生物技术分校，这阻碍了我继续接受Kakeni的资助。然而，我目前在京都大学担任外部研究员，这将使我能够最终确定这一项目的研究计划，并继续编写另外两份手稿，将在国际期刊出版物上发表。由于这些变化，我不能按计划参加国际会议。

In FY2017, I completed the global mapping of convergent scientific research, which included the processing of 1.5 million publications and 24,000 clusters across all fields of science. Building on this map, I selected three cases of highly convergent life science domains to examine their patterns of innovation: (a) the study of the factors influencing the evolution of emerging iPS cell-based therapies, (b) the examination of the evolution and patterns of collaboration in next-generation cancer immunotherapies, and (c) the assessment of convergence in Japan's WPI research centers. For these cases, we used a mixed-methods approach that includes scientific, technological and clinical data. Different domestic and international collaborations were built to conduct this research. Main outputs of this research are two manuscripts that are currently under review and will be added to this grant once they are accepted.A career change to a Kyoto University biotech spin-off in FY2017 impeded me to continue with my Kakenhi funding. However, my current affiliation at Kyoto University as an external research fellow will allow me to finalize the research plans of this project and to continue with the preparation of two additional manuscripts to be published in international journal publications. Owing to these changes, I was not able to attend international conferences, as planned.