An interpersonal group program for depression and work stress (IPT-Work) versus supportive psychotherapy: a multicentre, randomised, controlled trial

抑郁症在工作场所非常普遍，对社会和职业功能以及抑郁症员工的病假产生重大影响。与工作相关的压力被患者描述为抑郁症的最常见原因。在过去几年中，对遭受工作压力的员工进行心理社会干预受到越来越多的关注。然而，针对抑郁症患者的具体工作方法的研究却很少。由于工作压力在很大程度上是由社会心理因素驱动的，人际心理治疗（IPT）作为一种基于证据的抑郁症治疗的另一个新焦点，即“工作压力”（IPT- work），被概念化为治疗抑郁症和工作压力。由于工作通常发生在人际环境中，IPT-Work解决了社会心理压力源，如工作中的人际冲突、角色压力、低社会支持和减少压力工作条件。与常规治疗相比，该概念的试点数据首先显示出令人鼓舞的结果。本项目的目的是比较10期IPT-Work小组项目与非特异性支持小组治疗的疗效。总共有144名患有抑郁症和工作压力的患者将被调查。预计在治疗结束三个月后，与支持性心理治疗相比，IPT-Work在减轻抑郁症状和提高工作能力方面更有效。因此，IPT-Work项目可能有助于减少工作压力，提高工作满意度，并减少工作场所抑郁症患者的病假。

Depressive disorders are highly prevalent at the workplace and have a major impact on social and occupational functioning and on sick leave of depressed employees. Work related stress has been described as the most common cause of depression by patients. Psychosocial interventions for employees suffering from work related stress have received increasing attention in the past few years. However, there is only very little research on specific work focused approaches for depressed individuals. Since stress at work is driven largely by psychosocial factors, an additional novel focus of Interpersonal Psychotherapy (IPT) as an evidence-based depression treatment, namely "work stress" (IPT-Work), was conceptualized for the treatment of depression and work stress. As work usually takes place in an interpersonal context, IPT-Work addresses psychosocial stressors such as interpersonal conflicts at work, role stress, low social support, and the reduction of stressful working conditions. Pilot data for this concept show first encouraging results compared to treatment as usual. The goal of this project is to compare the efficacy of a 10-session IPT-Work group program with nonspecific supportive group therapy. Overall, 144 patients with depression and work stress will be investigated. It is expected that IPT-Work is more effective in reducing depressive symptoms and in increasing work ability compared to supportive psychotherapy three months after the end of treatment. The IPT-Work program may thus contribute to a decrease of work stress, an increase of work satisfaction, and reduced sickness absence in depressed individuals at the workplace.