Nonlinear Dynamics of Pulse Coupled Oscillators

基于简单的交互单元，将创建心脏起搏器系统的数学模型。这些单位已被证明是很好的生理信息模型，例如区分不同对心率的影响。我们将首先查看简单组合中各单元之间的相互作用，然后调整模型以模拟心脏起搏器的行为。 阐明导致心脏性猝死的心律失常的潜在机制可能会带来潜在的益处。并建议人工起搏器在异常心律转变为潜在致命的纤颤之前有效地阻止它们。

A mathematical model of the heart pacemaker system will be created, based on simple interacting units. These units have been shown to be good models of physiological information e.g. the discrimination of different influences on heart rate. We will firstly look at the interaction of the units in simple combinations and then tune the model to mimic the behaviour of the cardiac pacemaker. Potential benefits may arise from elucidating the mechanisms underlying arrhythmias which contribute to ?sudden cardiac death? in young men, and suggesting strategies for artificial pacemakers to effectively arrest abnormal rhythms before they convert to potentially fatal fibrillation.