New Methodology for the Stereoselective Construction of Oxygen Heterocycles and Rare Sugar Analogues.

这项研究的总体目标是开发新的合成方法，特别是那些表现出高水平立体控制的方法。目前的研究方向是利用含有栓系羟基的1，2-二恶英作为关键的化学前体来立体选择性地构建外消旋和手性形式的氧杂环和稀有糖类似物。预计这些研究将导致开发合成新的生物活性有机物的简单实验方案。

The overall goal of this research is to develop new synthetic methods, particularly ones that exhibit high levels of stereocontrol. Current research efforts are directed towards the stereoselective construction of oxygen heterocycles and rare sugar analogues both in their racemic and chiral forms utilising 1,2-dioxines containing tethered hydroxyl moieties as the key chemical precursors. It is envisaged that these investigations will lead to the development of simple experimental protocols for the synthesis of new bioactive organics.