Interfacial Studies of Nanoparticulate Dendrimers for Improved BioPharmaceutical Application
Interfacial Studies of Nanoparticulate Dendrimers for Improved BioPharmaceutical Application
批准号:
LP0455268
负责人:
Prof Clive Prestidge
金额:
$26.91万
依托单位国家:
澳大利亚
项目类别:
Linkage Projects
财政年份:
2004
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2004-09-10 至 2007-09-10
中文摘要
树枝状聚合物是一类新型的纳米颗粒,具有令人兴奋的潜力,作为药物用于预防主要疾病状态,例如病毒和癌症。 将采用胶体和界面化学方法来了解溶液到细胞转运过程的机制,并优化递送载体的制剂策略。 新药品的开发将取得重大进展,在国内和国际上带来重大的社会和经济效益。
英文摘要
Dendrimers are a novel class of nanoparticles with exciting potential as pharmaceuticals for the prevention of major disease states, e.g. viral and cancer. A colloid and interfacial chemistry approach will be employed to develop an understanding of the mechanisms for the solution to cell transport processes and for optimisation of formulation strategies for delivery vehicles. Significant advances in the development of novel pharmaceutical products will result, with significant social and economic benefits nationally and internationally.
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