Synthesis and Production of High Value Pyridines Combining the Concepts of Alternative Reaction Media and Process Intensification

该项目旨在通过汇集绿色化学和工艺强化领域的专业知识，开发取代吡啶的新合成和工艺路线。最大限度地减少浪费、提高能源效率以及改善选择性和控制将是生产高价值化合物的关键工艺和化学目标。传统的方法使用有机溶剂和预制盐，这些方法成本高、产生废物，而且由于选择性差、产率低和分离步骤繁琐，这些过程是能源密集型的。这是一项一般性的研究，在制药、能源和先进电子行业将有广泛的应用。

This project aims to develop novel syntheses and process route for substituted pyridines by bringing together expertise in the fields of green chemistry and process intensification. Minimisation of waste, energy efficiency, and improved selectivity and control will be the key process and chemistry targets, which will produce high value compounds. Traditional approaches use organic solvents and preformed salts which are costly, generate waste and the processes are energy intensive due to poor selectivity, low yield and extensive separation steps. This is a generic investigation which will have wide ranging applications in the pharmaceutical, energy and advanced electronic industries.