Targeted isolation of specific marine bacterial species associated with higher organsims for the purpose of discovering new antimicrobial compounds

与海洋动植物有关的特定细菌种类通常会产生活跃的次生代谢物。该项目的目的是将我们对这些细菌-宿主关联的理解应用于从海洋环境中有针对性地分离新型抗菌剂。虽然这些新化合物无疑将有许多商业应用，但该项目的重点是开发动物牙齿卫生产品。总体而言，迫切需要新的抗菌化合物来对抗越来越多的对当前抗生素产生抗药性的微生物，这突显了该项目的重要性。

Specific bacterial species that are commonly found in association with marine plants and animals often produce active secondary metabolites. The aim of this project is to apply our understanding of these bacterial-host associations to the targeted isolation of novel antimicrobials from the marine environment. While these new compounds will undoubtedly have a number of commercial applications this project focuses on the development of products for dental hygiene in animals. Generally, the urgent need for new antimicrobial compounds to combat the growing number of microbes that are resistant to current antibiotics highlights the importance of this project.