Comprehensive Study on the Effective Use of Laboratory Animals which have been Developed and held in Different Institutions

本次为期两年的合作研究结果表明，目前实验动物的信息、质量控制、运输等方面的方法最有利于不同机构之间的动物互用。(1)数据库的建设和使用。使用实验动物数据库最有效的是使用MS-DOS操作的磁盘，因为大多数机构都安装了由该系统操作的微型计算机，而不是在线操作的计算机系统。(2)动物质量控制。检测特定病原体抗体的酶联免疫试剂盒是一种简便有效的微生物质量控制试剂盒。本研究开发的一种简单的酶电泳仪可用于小鼠和大鼠的遗传质量控制。(3)动物运输。非冷冻胚胎和冷冻胚胎可以在机构之间移植。这些方法有望在未来用于动物的运输。

The results of this two-year co-operative research indicate that at the present the following methods on information, quality control, transportation of laboratory animals are best for the mutual utilization of the animals between the different institutions.(1) Construction and use of database. The distribution of diskette which is operated by MS-DOS is the most effective to use the database on the laboratory animals, because most institutions have installed microcomputers which operated by the system but not on-line operated computer system.(2) Quality control of animals. ELISA kit for the detection of the antibodies against the specific pathogens is simple and effective for microbiological quality control. Enzyme electrophoresis by a simple device which developed during this research could be used for genetic quality control of mice and rats.(3) Transportation of animals. Non-frozen and frozen embryos can be transferred between the institutions. The methods are promised future use for the transportation of animals.