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Development of a computation system to calculate temperature distribution for hyperthermic treatment

Development of a computation system to calculate temperature distribution for hyperthermic treatment
开发计算热疗温度分布的计算系统
批准号:
01570593
负责人:
NAKAJIMA Toshifumi
金额:
$1.34万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (C)
财政年份:
1989
资助国家:
日本
项目状态:
已结题
起止时间:
1989 至 1991

项目摘要

项目成果

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中文摘要
翻译
温度决定了对热疗的反应,并且需要了解患者体内的温度分布以有效地进行这种治疗并评估其效率。开发了一个计算病人体内温度分布的系统。它由一台16位的个人计算机和一个40MB的硬盘组成,并计算了一个二维的温度分布在一个病人加热的射频电容加热单元。稳态和非稳态温度分布计算从CT数据通过使用有限元方法。在输入CT数据后约10分钟内可获得稳态温度分布。非稳态温度分布计算所花费的时间等于治疗患者所需的时间。尽管定量评价仍存在问题,但该系统提供了对临床治疗有用的信息。三维温度场计算程序 ...更多信息 通过与计算机中心的电话连接使用考虑治疗期间BLBOD流量变化的URE分布和非线性计算机程序。然而,这个系统被认为是不适合在医院使用,因为它需要太多的时间来传输数据和系统的维护是困难的。已经开始开发一种可用于组织循环研究的系统。我们研究了几种计算机程序,但对用于计算温度分布的参数知之甚少。热疗过程中的血流已经做了大量的工作,热扩散法,它测量血液流动的热疗过程中获得的洗脱曲线,被认为是实用的方法。然而,对其他参数的研究很少。开发了一个可用于医院的热模型原型。一旦我们熟悉了它,我们就可以提供基础数据,将系统改进到可以进行定量估计的阶段。少
英文摘要
Temperature determines responses to hyperthermic treatment, and knowledge of the temperature distribution in a patient is required for carrying out such treatment efficiently and for assessing its efficiency. A system to calculate temperature distribution in a patient was developed. It consists of a 16-bit personal computer and a 40MB hard disk and Calculates a two-dimensional temperature distributibn in a patient heated with a RF capacitive heating unit. Both steady state and non-steady state temperature distributions were calculated from CT data by using a finite element method. A steady state temperature distribution could be obtained in about 10 minutes after the input of the CT data. A non-steady state temperature distribution calculation took an amount of time equal to that needed to treat the patient. Although quantitative evaluation remains problematic, the system provides imformation useful for clinical tratment. The computer programs for calculating three-dimensional temperat … More ure distribution and non-linear computer programs which consider changes in blbod flow during treatment were used via telephone connection to a computer center. Howevdr, this system was regarded as unsuitable for use at hospitals because it took toomuch time for data transfer and maintenance of the system was difficult. Development has begun on a system which can be used in research on tissue circulation. We investigated several kinds of computer programs but had lottle information about the parameters used for calculation of temperature distribution. Much work has been done on blood flow during hyperthermia, and the thermal diffusion method, which measures blood flow from washout curves obtained during hyperthermic treatment, was found to be practical method. However, little investigation has been done on other parameters. A prototype of thermal modeling was developed which could be used at hospitals. Once we become familiar with it, we can offer fundamental data for improving the system to a stage where quantitative estimation is possible. Less
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会议论文
中島 俊文: "局所加温がラット諸臓器血流量に及ぼす影響" 日本ハイパ-サ-ミア誌. 6. 139-147 (1990)
Toshifumi Nakajima:“局部加热对大鼠各器官血流的影响”日本热疗杂志 6. 139-147 (1990)。
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津村 昌: "ハイパ-サ-ミア治療3年以上生存例の検討" 日本ハイパ-サ-ミア誌. 6. 159-167 (1990)
Masaru Tsumura:“热疗治疗后存活 3 年或以上的病例研究”《日本热疗杂志》6. 159-167 (1990)。
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