DEVELOPMENT OF MULTIPURPOSED PEDIATRIC BLOOD PUMP AND ITS DRIVING AND AUTOMATIC CONTROL MACHINE

介绍了一种由成人血泵改造而成的多用途小儿血泵及其驱动和自动控制单元的小型化。在模拟循环和实验动物上测试了泵以及驱动和控制单元的功能、安全性和耐用性。证实了血泵及其驱动控制单元能够根据静脉回流自动增加输出量，在流出道阻力增加时保持输出量，在流出道突然阻塞时停止泵送。虽然我们无法成功挽救这些婴儿的生命，但我们证实该系统的工作令人满意。实验上我们知道高流量ECMO会导致冠状动脉血流减少。自动血泵系统成功地灌注了肝脏，该系统将用于不能手术的肝脏恶性肿瘤的手术、化疗。我们现在正在开发一种新的血泵，它使用由聚氨酯制成的管状血室，带有一个新的光电传感器以及一个便携式驱动和控制单元。

A multipurposed pediatric blood pump and its driving and automatic control unit, which had been developed from an adult blood pump was miniaturized. Function, safety, and durability of the pump and the driving and control unit were tested on a mock circulation and on experimental animals. It was confirmed that the blood pump and the driving and control unit are capable to increase the output according to the venous return automatically, to keep the output against increasing resistance in the outflow tract, and to stop pumping when the outflow tract is suddenly obstructed.Our new ECMO circuit were used on 3 newborns with severe respiratory distress during the 3 year period. Although we could not success in saving lives of these infants, we confirmed that the system works satisfactorily. Experimentally we knew that high flow ECMO results in decrease in the coronary arterial flow. The liver was perfused successfully with the automatic blood pump system, which will be used for surgery, chemotherapy for inoperable malignancies of the liver. We are now developing a new blood pump using a tube shaped blood chamber made of polyurethan with a new photo-sensor and also a portable driving and control unit.