The study of severe maxillofacial disorders
The study of severe maxillofacial disorders
批准号:
05045045
负责人:
ETO Kazuhiro
金额:
$3.84万
依托单位国家:
日本
项目类别:
Grant-in-Aid for international Scientific Research
财政年份:
1993
资助国家:
日本
项目状态:
已结题
起止时间:
1993 至 1995
中文摘要
将小鼠胚胎前脑和中脑的神经嵴细胞分别进行培养,并进行免疫组织化学鉴定。中脑培养的神经元多于前脑培养的神经元。仅在中脑培养物中发现被认为是软骨细胞的细胞,而在前脑培养物中观察到黑素细胞。这些结果意味着,从两个区域的差异潜力似乎是部分限制迁移之前,从neuroepithelium.The严重颌面部疾病的手术有关的调查,在两个医疗机构,并在过去10年的数据进行了比较。恶性肿瘤中最大的一组是鳞状细胞癌,超过40%发生在泰国的下颌骨和日本的舌头上。在所有良性肿瘤中,成釉细胞瘤(51.4%)在泰国占最大比例,血管瘤(18.8%)在泰国占最大比例。 ...更多信息 日本单侧唇腭裂是最常见的畸形在这两个国家。在颌面部骨折的资料中,男性几乎是女性的3倍。骨折的主要原因在泰国为交通事故(72.5%),在日本为跌倒(30.0%)。关于TMJ功能障碍,泰国手术治疗强直(87.5%)和髁突增生(12.5%)。根据病理条件,日本采用了几种手术方法。对泰国和日本严重颌面部疾病患者进行了临床统计学研究。比较两所正畸治疗前后患者资料及口腔颌面部修复护理情况,发现两所正畸治疗在许多方面存在显著差异,主要是基于经济状况的差异。本研究中使用了21个头影测量参数。在两个样品中发现了一些相似之处,然而,也认识到一些差异。治疗后,泰国患者的下门牙向舌侧倾斜程度更高,前牙高度增加更多。对Papillon-Lefevre综合征(PLS)患者进行了检查和治疗。用ELISA法检测患者对伴放线放线杆菌(Actinobacillusactinomycetemcomitans(A.a.)处理后A.a.减少,细菌培养物中未检测到A.a.。PLS患者对A.a.a.的同一抗原均呈阳性反应,A.a.可能在PLS患者牙周组织破坏中起一定作用。少
英文摘要
Neural crest cells derived from forebrain and midbrain of mouse embryos were cultured separately and performed immunohistochemistry to identify the characteristics of the differentiated cells. Neurons derived from midbrain cultures were more than those from forebrain cultures. Cells which supposed to be chondrocytes were found only in midbrain cultures and melanocyte cells were observed in forebrain cultures. These results mean that the differential potentialities from the both regions seemed to be partly restricted before migrating out from the neuroepithelium.The severe maxillofacial disorders related to the surgery were investigated in two medical facilities and the data during the past 10 years was compared each other. The largest group in malignant tumors was represented by squamous cell carcinoma and more than 40% occurred on the mandible in Thailand and on the tongue in Japan. Of all benign tumors ameloblastoma (51.4%) made the largest group in Thailand and hemangioma (18.8%) in … More Japan. Unilateral cleft lip and palate was the most frequent malformation in both countries. In the data of the maxillofacial fractures men were almost 3 times as many as women. The fractures were caused mainly by traffic accident (72.5%) in Thailand and by fall down (30.0%) in Japan. Concerning TMJ dysfunction ankylosis (87.5%) and condylar hyperplasia (12.5%) were treated surgically in Thailand.Depending on the pathologic conditions several surgical procedures applied in Japan.A clinico-statistical study was performed on patients with severe maxillofacial disorders in Thailand and Japan. Data on the patients and maxillofacial prosthetic cares for them were compared between the two, conspicuous difference was found in many respects that mainly based on the economic status of the nation.A comparative cephalometric study was carried out by using pre- and post surgical orthodontic treatment in both institute. There were 21 cephalometric parameters used in this study. Some similarities in both samples were found, however, a few differences were also recognized. More lingually inclined lower incisor and more increased anterior dental height were found in Thai patient after treatment.Papillon-Lefevre syndrome (PLS) patients were examined and treated. The ELISA titers of the patients against Actinobacillus actinomycetemcomitans (A.a.) decreased after treatment and A.a.could not be detected in bacterial cultures. PLS patients showed positive antibody response to the same antigens of A.a.A.a.seemed to play role to periodontal tissue destruction in PLS patients. Less
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Hasegawa, K., Amagasa, T.: "Oral and Maxillofacial reconstruction using free rectus abdominis myocufaneous flap" J.Cranio-Maxillo-Facial Surg.22. 236-243 (1994)
Hasekawa, K., Amagasa, T.:“使用游离腹直肌肌瓣进行口腔颌面重建”J.Cranio-Maxillo-Facial Surg.22。
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Yoshiyuki BABA,Takafumi SUSAMI,Masamitsu UJI,Keiji MORIYAMA,Rong Rong MA,Makoto YAMAMOTO,Nobuyuki MOTOHASHI and Takayuki KURODA: "Topographical relationships between teeth and alveolar arches in patients with unilateral cleft lip and palate after orthodon
Yoshiyuki BABA、Takafumi SUSAMI、Masamitsu UJI、Keiji MORIYAMA、Rong Rong MA、Makoto YAMAMOTO、Nobuyuki MOTOHASHI 和 Takayuki KURODA:“单侧唇腭裂患者正畸后牙齿与牙槽弓的地形关系
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加藤嘉之、天願俊永、清水利江子、宇治正光、本端信義、黒田敬之: "顔面非対称症例の正面頭部X線規格顎分析" 日本顎変形症学会雑誌. 4. 87-95 (1994)
Yoshiyuki Kato、Toshinaga Tengan、Rieko Shimizu、Masamitsu Uji、Nobuyoshi Honbata、Noriyuki Kuroda:“面部不对称病例的前头 X 射线标准化颌分析”日本颌畸形协会杂志 4. 87-95 (1994)。
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T.Susami,T.Kuroda: "Quantitative evaluation of the shape and the elasticity of repaired cleft lip" Cleft Palate-Craniofacial J.30. 309-312 (1993)
T.Susami,T.Kuroda:“唇裂修复的形状和弹性的定量评估”Cleft Palate-Craniofacial J.30。
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天笠光雄: "先天性上唇正中瘻の2例" 日本口蓋裂学会雑誌. 18. 381-385 (1993)
Mitsuo Amagasa:“先天性中线上唇瘘的两例”日本裂腭协会杂志 18. 381-385 (1993)。
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共 36 条
The better isolation and detection methods of cranial neural crest stem cells (CNCSC) and the therapeutic potentiality of CNCSC in the treatment of craniofacial abnormalities.
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批准号:13357015
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$32.03万
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财政年份:2001
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负责人:ETO Kazuhiro
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依托单位:
Investigation of organaizers in vertebrate craniofacial development
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批准号:10307043
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$26.3万
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财政年份:1998
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负责人:ETO Kazuhiro
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依托单位:
The establishment of a new type of long-term culture system in which the whole embryo cultu lowed by a mandibular organ culture.
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批准号:08557097
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$12.8万
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财政年份:1996
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负责人:ETO Kazuhiro
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依托单位:
Developmental Biotechnological Analysis of Craniofacial Malformation in Mutant Rat and Mouse.
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批准号:06454520
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.54万
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财政年份:1994
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负责人:ETO Kazuhiro
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依托单位:
Analysis for a transgenic mouse with facial malformations.
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批准号:02454414
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.03万
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财政年份:1990
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负责人:ETO Kazuhiro
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依托单位:
The study of neural crest cells by the mammalian whole embryo culture
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批准号:61870073
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项目类别:Grant-in-Aid for Developmental Scientific Research
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资助金额:$1.92万
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财政年份:1986
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负责人:ETO Kazuhiro
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依托单位:
海外基金