Co-operative Research on Clinical Application of Heart and Heart-Iung Transplantation

Kaihara开发的“日本移植信息网络系统”是一种新的多器官共享网络系统，比传统的主框架更适合实现所需的功能。Kawashima对70例扩张型心肌病进行了研究，认为左室扩张和心肌显像大缺损是有效的预后指标。Toshima报道了对36名潜在心脏移植候选者的随访研究，并指出需要反复评估。Matsuda通过对心脏移植术后CMV感染病例的研究，制定了心脏移植患者的快速诊断系统和临床适用的治疗方案。还报道了脑死亡患者的心脏表现。其他研究者多从事实验研究，报道了新的单克隆抗体，如抗icam -1和抗lfa -1抗体，抗t细胞受体α - β抗体；心脏停跳1小时供体心脏移植；心脏排斥反应的新诊断方法心脏不协调免疫抑制的新免疫抑制。

Kaihara developed "information Network System for Transplantation in Japan", which is a new network system for multi organ sharing and more appropriate to implement required features than a classical main frame. Kawashima studied seventy cases of dilated cardiomyopathy and recognized the left ventricular dilatation and large defect in myocardial scintigraphy as useful prognostic indices. Toshima reported the follow-up study of thirty-six potential candidates for cardiac transplantation and pointed out the need for repeated evaluation. Matsuda studied post surgical cases with CMV infection and developed the prompt diagnostic system and clinical applicable treatment protocol for cardiac transplant patients. Cardiac performances of the brain dead patients were also reported. Other investigators were mostly engaged in experimental studies and reported new immunosuppression with new monoclonal antibodies such as anti-ICAM-1 and anti-LFA-1 antibodies, anti-T cell receptor alpha beta antibody ; cardiac transplantation from the donors with one hour after cardiac stand still ; new diagnostic method for cardiac rejection ; new immunosuppression for cardiac discordant immunosuppression.