Comparative study of ATL and HTLV-I Related Disorders

目前尚无中国内地高危人群HTLV-I型血清阳性率调查。为了了解天津市高危人群中HTLV-I的血清阳性率，我们进行了调查。我们完全是。采集白血病、神经系统疾病、肝炎患者和献血员血清标本898份。只有一名患者血清HTLV-I呈阳性。天津危险人群中国的感染率很低，与其他非流行国家相当。(中国)我们调查了27名来自圣保罗的HTLV-I无症状携带者，并进行了眼科检查，以寻找葡萄膜炎。危险因素为多次输血、静脉吸毒和母亲感染。我们在5例患者中发现了角膜侵蚀、脉络膜视网膜和棉花，这些发现与Mochizuki等人报道的HTLV-I葡萄膜炎相一致。(巴西)对居住在大西洋沿岸科尔特斯港的62名黑人和居住在圣佩德罗苏拉的52名妓女的114份血清样本进行了HTLV-I/II抗体检测。黑人人口的流行率为17.7%，完全是由HTLV-I引起的。唯一的HTLV-II感染病例来自一名没有危险因素且艾滋病毒阴性的妓女。(洪都拉斯)我们分析了一个家庭(美洲印第安人后裔)的样本，这些家庭出生在哥伦比亚南部靠近卡利市的安第斯山脉，目前住在蔡。一名35岁的女性献血者在血库中被检测为HTLV-I/II携带者。她的父母也是HTLV-II血清阳性者，这些捐赠者没有症状和健康，有输血、手术、纹身、静脉注射药物和/或迁移到HTLV-II流行区的负面故事。这一HTLV-II感染家族性病例使我们可以推测，水平传播发生在配偶身上，垂直传播发生在母亲和女儿之间。这是在血库筛查中发现的第一例HTLV-II携带者。(哥伦比亚)

Until now there is no any investigation of HTLV-I seroprevalence in risk populations in mainland of China. To know the seroprevalence of HTLV-I in risk populations in Tianjin, we performed the survey. We totally. collected 898 serum samples from leukemia, neurological diseases and hepatitis patients and blood donors. Only one patient's serum was positive for HTLV-I.The prevalence in risk groups from Tianjin, China, is low and comparable to other non-endemic countries. (China)We have investigated 27 HTLV-I asymptomatic carriers from Sao Paulo, with ophthalmological examinations searching for uveitis. The risk factors were multiple blood transfusions, intravenous drug use and infected mothers. We found corneal erosion and chorioretinal and cotton wool in 5 cases, the findings consistent with HTLV-I uveitis reported by Mochizuki et al. (Brazil)114 sera samples, 62 of black population, living in Puerto Cortes, Atlantic Coast and 52 of prostitutes living in San Pedro Sula were tested antibodies for HTLV-I/II.The prevalence of the black population is 17.7% and exclusively due to HTLV-I.The only case of HTLV-II infection came from a prostitute with no risk factor and HIV negative. (Honduras)We analyzed samples from a family (Amerindian descendants) that were born in Colombia's southern Andes near the city of Cali and are living in Cai. A 35-yrs-old woman donor was detected as a HTLV-I/II carrier in the blood bank. Her parents were also seropositive to HTLV-II.Those donors are asymptomatic and healthy, with a negative story of transfusion, surgery, tattoo, intravenous drugs, and/or migration to HTLV-II endemic areas. This familial case of HTLV-II infection permits us to speculate that horizontal transmission had occurred in the spouses, and vertical transmission occurred from mother to daughter. This is the first case of a HTLV-II carrier detected in blood bank screening. (Colombia)