Revealing the mechanobiology of neural tube formation

这个项目旨在了解神经管的形成；神经管是产生大脑和脊髓的基本组织结构。利用跨学科的方法，利用转基因和成像技术的最新进展，我们希望揭示细胞与其环境之间的复杂相互作用，这种相互作用产生机械力来指导神经组织的形成。成果包括了解以前难以解决的发展过程、培训未来的科学家以及发展国际合作。这将提供增强的成像能力，更高素质的科学劳动力，并使澳大利亚处于细胞和发育生物学的前沿。

This project aims to understand the formation of the neural tube; a fundamental tissue structure that generates the brain and the spinal cord. Using interdisciplinary approaches and exploiting recent advances in transgenic and imaging technologies, we expect to reveal the complex interplay between cells and their environment that generates mechanical forces to direct neural tissue formation. Outcomes include knowledge of previously intractable developmental processes, training of future scientists and development of international collaborations. This should provide enhanced imaging capacity, a higher quality scientific workforce and position Australia at the forefront of cell and developmental biology.