Prophyractic photocoagulation for serous drusen

我们凝结了软性玻璃体，人们强烈怀疑它容易发生渗出性老年性黄斑变性。在随访期内，22只眼中有14只眼(%)黄斑区软性玻璃体消失。14只眼中1只眼光凝诱导脉络膜新生血管形成。14只眼中另一只眼中心凹内视网膜色素上皮和脉络膜毛细血管萎缩。在黄斑萎缩发生之前，这只眼已经表现出色素改变，我们还对符合相同标准的89名患者的98只眼进行了随访，这些患者的软性玻璃体没有凝结。脉络膜新生血管11只眼(11%)。累积发病率估计一年为3%，三年为39%，五年为%。尽管未经治疗的眼发生CNV的发生率很高，但我们所进行的光凝治疗似乎不适合软性玻璃体患者的治疗。

We coagulated soft drusen which was strongly suspected of being predisposed to exudative age-related macular degeneration. During the follow-up period, soft drusen in the macular region disappeared in 14 of the 22 eyes (64%) in the study. Choroidal neovascularization was induced in one of these 14 eyes by photocoagulation. Retinal pigment epitheliumchoriocapillaris atrophy in the fovea developed in another of the 14 eyes. This eye had shown pigmentary change before this foveal atrophy occured We also followed up 98 eyes of 89 patients who met the same eligibility criteria but whose soft drusen was not coagulated. Choroidal neovascularization appeared in 11 eyes (11 %). Accumulative incidence was estimated to be 3% at one year, 39% at three years, and 64% at five years. Although the incidence of developing CNV in untreated eyes is high, the photocoagulation which we performed seems an inappropriate treatment for patients with soft drusen.