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Gene Analysis of Cardiac ion channel genes on Sudden Infant Death Syndrome (SIDS) and Youth Sudden Death.

Gene Analysis of Cardiac ion channel genes on Sudden Infant Death Syndrome (SIDS) and Youth Sudden Death.
婴儿猝死综合症(SIDS)和青少年猝死的心脏离子通道基因的基因分析。
批准号:
11670427
负责人:
SAITO Kazuyuki
金额:
$2.24万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
1999
资助国家:
日本
项目状态:
已结题
起止时间:
1999 至 2001

项目摘要

项目成果

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中文摘要
翻译
在1999年和2000年,对婴儿猝死综合征(SIDS)病例进行了心脏离子通道基因区的PCR-SSCP分析。在2001年度,对eucrasia对象组和SIDS病例进行了心脏离子通道基因区域的遗传分析。然后将SIDS病例与正常对照组的分析结果进行比较和检验。2 SIDS组与正常对照组之间LQT-3基因区和LQT-2基因区DAN多态性分布结果无显著性差异。也就是说,SIDS病例不能识别LQT-2和LQT-3基因的相关性。并对所有诊断为SIDS的病例进行了遗传学分析、死亡时的旁证调查和病理形态学检查
英文摘要
On the Sudden Infant Death Syndrome (SIDS) case, PCR-SSCP analysis of the heart ion channel gene region was carried out in fiscal 1999 and 2000. In fiscal 2001, the genetic analysis of the heart ion channel gene region was carried out on the eucrasia object group as well as the SIDS case. Then, SIDS case and analytical result of the normal contrast group were compared and were examined. 2 intergroup between SIDS and normal contrast group could not recognize the significance the result for DAN Polymorphism distribution in LQT-3 gene region and LQT-2. That is to say, the SIDS case could not recognize LQT-2 and relevance to the LQT-3 gene. And, all cases were diagnosed as SIDS on all SIDS cases of the genetic analysis, when death circumstantial investigation and pathomorphological case examination were carried out
期刊论文(3)
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会议论文
齋藤一之, 高田綾: "突然死例にみる脳動脈瘤と動脈解離"医学のあゆみ:動脈瘤と動脈解離の最前線. 別冊. 111-115 (2001)
Kazuyuki Saito,Aya Takada:“猝死病例中的脑动脉瘤和动脉夹层”医学史:动脉瘤和动脉夹层的前沿特卷111-115。
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通讯作者:
T Murai, K Saito et al.: "Sudden death due to cardiovascular disorders : a review of the studies on the medico-legal cases in Tokyo"Keio J Med.. 50. 175-181 (2001)
T Murai, K Saito 等:“心血管疾病引起的猝死:东京法医案例研究回顾”Keio J Med.. 50. 175-181 (2001)
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通讯作者:
Aya Takada, et al: "Papillary fibroelastoma of the aortic valve : a sudden death case of coronary embolism with myocardial infarction"Forensic Science International. 113. 209-214 (2000)
Aya Takada 等人:“主动脉瓣乳头状弹力纤维瘤:冠状动脉栓塞伴心肌梗死的猝死病例”国际法医科学。
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通讯作者:
Development of hybrid electrical scalpels combining microwave and high frequency current
  • 批准号:
    15K06010
  • 项目类别:
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  • 资助金额:
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  • 财政年份:
    2015
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  • 资助金额:
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  • 财政年份:
    2012
  • 负责人:
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Development of thin microwave antenna inserted into endoscope for treatment of bile duct carcinoma
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    22760242
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
  • 资助金额:
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    2010
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A study of a method to improve the productivity of mixed semiconductor manufacturing
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    15560350
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $1.09万
  • 财政年份:
    2003
  • 负责人:
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  • 依托单位:
海外基金