The experimental study of the tendor repair

近年来，对组织再生的研究已成为医学领域的研究热点之一。肌腱组织很强壮，由丰富的胶原纤维组成。然而，肌腱的愈合过程尚不清楚。在本研究中，我们重点研究了生长因子对加速修复过程的作用。首先，我们希望利用免疫组织学染色和原位杂交技术来确定修复细胞和生长因子在肌腱愈合过程中的表达特征和时间。分析TGF-β、FGF、型胶原、型胶原的表达时间。研究结果如下：TGF-β在术后1周和2周表达量最大。FGF的表达不断达到高峰。同时，型胶原蛋白的表达也成为高峰。型胶原蛋白的表达不断达到高峰。因此，应确定各生长因子的最佳浓度和面积、方法。

Recently, the study for the tissue regeneration has become one of the topics of the research of the medical field. The tendon tissues are strong and consists of rich collagen fibers. However, the healing process of the tendon is unknown. In this study, we have focused on the growth factor for the accelerating the repair process. At first, we would like to identify the character and time of the expression of the reparative cells and growth factors in the healing process of the tendon using immunohistological staining and in situ hybridization procedure.We analyzed the time of expression of TGF-β and FGF, Type collagen , Type collagen.The results are as follows ; The TGF-β has showed the maximum expression at the period of 1 and 2 weeks after surgery. Continuously the expression of FGF has become the peak. At the same time, the expression of the Type collagen has become the peak. Continuously the expression of Type collagen has become the peak.Consequently we should establish the optimum concentration and area, method of each growth factor.