Effect of Gingival Stimulation with a Toothbrush on Periodontal Diesease.

对16例牙周病患者进行SPT期牙龈刺激（GS）治疗。GS应用于附着龈，探测深度为4 ~ 6mm。采用标准化方式对患者进行GS技术培训，并要求患者在常规刷牙后1个月左右在试验点（ES， 30个点）使用GS技术。在对侧，他们被要求仅使用常规方法作为对照位点（CS， 19个位点）。实验前后分别进行牙龈微循环功能（GMF）的临床评估和测量。ES组（2.0 ~ 1.4）和CS组（2.1 ~ 1.7）牙龈指数评分下降。ES组显著降低（p=0.0013）， CS组接近显著水平（p=0.0520）。ES组和CS组斑块指数评分无明显变化。ES组（4.3mm-3.9mm, p=0.0007）和CS组（4.6mm-4.0mm, p=0.0002） PD显著降低。两个地点的依恋水平没有显著变化。龈沟液流量（65.0 ~ 47.4,p=0.0020）和龈窝温度（35.6 ~ 35.9,p=0.0418）在龈沟液流量（65.0 ~ 47.4,p=0.0020）和龈窝温度（35.6 ~ 35.9,p=0.0418）参数中均有显著变化。上述结果表明，甘草多糖具有改善牙龈微循环功能的作用，可能有助于牙周症状的恢复

Effect of gingival stimulation (GS) with a toothbrush on periodontal disease was investigated in 16 periodontal patients during SPT phase. GS was applied to attached gingiva with probing depth (PD) of 4-6mm. The patients were trained for GS with a standardized manner and were asked to use the GS technique at experimental sites (ES, 30 sites) following their routine tooth brushing for about 1 month. In the contra lateral side, they were asked to use only their routine method for use as control sites (CS, 19 sites). Clinical assessments and measurements of gingival microcirculatory function (GMF) were performed before and after the experimental period. The Gingival index score decreased in ES (2.0-1.4) and CS (2.1-1.7). The decrease was significant in ES (p=0.0013) and approached significant level in CS (p=0.0520). No significant change was found for the Plaque index score in ES and CS.PD decreased significantly in ES (4.3mm-3.9mm, p=0.0007) and CS (4.6mm-4.0mm, p=0.0002). Attachment level did not change significantly in both sites. Among parameters of GMF, significant changes occurred in gingival crevicular fluid flow (65.0-47.4, p=0.0020) and pocket temperature (35.6-35.9, p=0.0418) in ES only. These result indicated that GS could improve gingival microcirculatory function, and suggested that GS might contribute to recovery of periodontal symptom