Efficacy of care and treatment for emotional dysfunctions of drug abusers ; consideration of psyche-biological aspects.

目的：本研究的目的是探讨生物心理和精神方面的功能障碍之间的关系，观察在substance abusers.Methods：我们评估了51个物质滥用者居住在DARC（药物成瘾康复中心），一个长期的住宅设施，专门为滥用者在日本的特点。为了进行评估，我们使用以下测量，MRI，WCST，VFT和BVRT用于生物学方面; PANSS和POMS（情绪状态特征）用于精神/心理方面; PIL（生活目的测试）用于精神方面; ASI和SDS（依赖严重程度量表）用于成瘾相关问题。结果与结论^长期滥用有机溶剂的受试者通常表现出较差的认知表现。其中，戒断时间越长的被试，其认知成绩越高，PIL得分越低。结果表明，随着认知功能的恢复，一些虐待者可能会意识到他们的“无力感”，这可能导致灵性减弱。

Objective : The purpose of this study is to examine the relationships between bio-psychological and spiritual aspects of dysfunctions observed in substance abusers.Methods : We evaluated characteristics of 51 substance abusers residing in DARC(Drug Addiction Rehabilitation Center), a long term residential facility specialized for abusers in Japan. To evaluate, we used following measures, MRI, WCST, VFT and BVRT for biological aspects ; PANSS and POMS (Profile of Mood States) for psychiatric/psychological aspects; PIL(Purpose in Life Test) for spiritual aspects ; ASI and SDS(Severity of Dependence Scale) for addiction-related problems. Results and Conclusions^ The subjects with long history of organic solvent abuse generally showed poor cognitive performance. Among them, however, the subjects with longer abstinence period showed higher cognitive performance and lower PIL scores. The results suggest that, with recovery of cognitive functions, some abusers may become conscious of their 'powerlessness' which could lead to a weakening of spirituality.