A trial to elucidate neural mechanism of language information processing in perceptual executive system.

本研究试图探讨神经知觉执行系统中认知与词语表达的关系。4名健康右利手志愿者(男2名，女2名)参加本研究。使用脑磁图(MEG)测量了进行封顶动作(日语称为SHIR1TORI)时的磁场。记录控制会话(被动听音调或观看闪光刺激，在范式会话中作为线索刺激)和范式会话(在每个线索刺激发出后立即按SHIRITORI方式逐个产生单词)的反应，离线平均后进行分析。平均磁场的均方根(RMS)显示，与对照组相比，平均磁场在一定的潜伏期内增加，闪光和音调刺激开始后的潜伏期分别为380毫秒到930毫秒和300毫秒到820毫秒。此外，据报道，这些潜伏期的估计偶极子位于常规PET和fMRI研究报告的左半球一些与语言相关的区域，包括额盖、梭形和后下颞区。

This time we attempted to explore the relation of cognition and word expression in neural perceptual executive system. Healthy right handed 4 normal volunteer (man 2, woman 2) were participated to this study. The magnetic fields while performing capping verses (called "SHIR1TORI" in Japanese) were measured by using magnetoencephalography (MEG). Responses of control session (passive hearing of tone or viewing of flash stimuli, which were used as cue stimuli in the paradigm session) and paradigm session (mental generation of words one by one according to "SHIRITORI" manner immediately after each cue stimulus emission) were recorded, then analyzed after off-line averaging. Root mean square (RMS) of averaged magnetic fields in the paradigm session delineated its increase at some latencies as compared with control one, which latencies after flash and tone stimulus onset ranged from 380msec to 930msec and 300msec to 820msec, respectively. In addition, estimated dipoles of these latencies were located to some language-related area of left hemisphere reported conventional PET and fMRI studies, including frontal operculum, fusiform and posteroinferor temporal region.