Studies on the Function of Junctional Epithelium and the Mechanism of Epithelial Attachment

为探讨交界上皮的功能及其附着机制，主要采用组织学和免疫组织化学方法，观察了人牙龈交界上皮的形态特征，发现交界上皮细胞间隙较宽。这些细胞间隙似乎降低了咀嚼时连接上皮所受的机械压力。附着在牙齿表面的上皮细胞具有大量的细胞器和颗粒状结构。此外，由于在牙本质侧的细胞膜附近可见大量的细胞膜和囊泡的折叠，这些细胞似乎合成了某种物质，并进行了旺盛的吸收和分泌。至于面对牙齿的上皮细胞的半桥体、基底膜和细胞膜，证实其成为构成牙齿角质层的成分的可能性很高。通过连接上皮细胞之间的破坏导致牙周袋扩张在形态上变得清晰起来

To investigate the function of the junctional epithelium and the mechanism of epithelial attachment, I chiefly observed a morphological feature of human teeth and gingiva by histological and immunohistochemical technique.A comparatively wide intercellular space was seen in junctional epithelium. It seemed that these intercellular space decreased mechanical pressure that the junctional epithelium receive while masticating. The epithelial cells that attach to the tooth surface have a lot of cell organelles and granular structures. Moreover, because a lot of infoldings of cell membrane and vesicles are observed near the cell membrane of the dentine side, it seems that these cells synthesize a certain kind of substance, and do absorption and the secretion vigorously. As for the hemidesmosome, basal lamina and the cell membrane of the epithelial cell that faced tooth, it was confirmed that the possibility to become a part of element that composed dental cuticle was high. Causing the expansion of the periodontal pocket by the disruption between junctional epithelial cells became clear in morphology