Research of the temporal discrimination learning and EEG pattern in rats.

本研究的目的是通过电生理活动来评估不同脑区在时间分辨学习中的作用。时间分辨学习是行为最重要的特性之一，它包含在时间上。动物时间知觉的研究主要有三种方法，即时间分辨或时间分割程序、时间分化程序(如DRL、DRLL)和峰值间隔(PI)程序。我有三个实验，分别是时间分辨2秒和8秒，DRLL4秒程序，和峰值间隔30秒程序。我得到的结果是，所有的方法都可以达到学习的标准，没有任何问题。2003年4月，我在《日本生理心理学和心理生理学》上发表了一篇文章。脑电是通过与某些时间决策过程相关的大脑活动来反映的。可以通过测量…来研究大脑对外部刺激反应的变化更多的诱发电位。内部刺激，例如对时间标准的判断，会引起偶数相关电位(ERP)。刺激起始事件相关电位由P2、N2样成分和P3样成分组成。在额叶皮质和海马CA1区持续观察到类P3成分。与简单的反应时间任务相比，在时间辨别任务中观察到的类P3成分的幅度要大得多。在刺激偏移量时，P2、N_2和P_3样成分以及刺激开始时被诱发。在刺激偏移量时，时间辨别任务的额叶皮质类P3成分大于简单反应时间任务。我还计算了海马区的功率谱。在听觉刺激开始时，时间辨别任务的海马theta能力比时间控制任务增加的更多。我在2002年的神经科学会议上发表了论文，题目是时间行为和光驱动对大鼠脑电的影响。我发表了一篇关于工作记忆和时间信息处理的论文。较少

The purpose of this study is to evaluate the roles of various brain regions in temporal-discrimination learning by using electrophysiological activity. Temporal-discrimination learning which include in timing is one of the most important properties of behavior. There are three major methods to study time perception in animals, this is, temporal-discrimination or temporal-bisection procedure, temporal-differentiation procedure (e. g. DRL, DRLL), and peak-interval (PI) procedure. I had three experiments that were temporal-discrimination between 2-sec and 8-sec, DRLL 4 sec schedule, and peak-interval 30-sec procedure. I had the results that all method could reach the criterion in learning without any problem. I published an article in Japanese Physiological Psychology and Psychophysiology in April 2003.EEG is reflected by the brain activity associated with certain temporal decision processes. Changes in brain responsiveness to an external stimulus can be investigated by the measurement of … More evoked potentials. An internal stimulus such as the judgment of a temporal criterion will evoke an even-related potential (ERP). The stimulus onset ERPs consisted of P2, N2, and P3-like components. P3-like component was consistently observed for the frontal cortex and hippocampal CAI. Significantly greater amplitudes of the P3-like components was observed during the temporal-discrimination task when compared to the simple reaction-time task. At the stimulus offset, P2, N2, and P3-like components were elicited as well as the stimulus onset. P3-like component in the frontal cortex at the stimulus offset was larger for the temporal-discrimination task than for the simple reaction-time task. I also calculated hippocampal power spectra. The hippocampal theta power increased more in the temporal-discrimination task than in the temporal control task at the onset of the auditory stimuli. I presented at the neuroscience meeting in 2002 entitled timing behavior and photic driving on EEG in rats. I published a paper dealing with working memory and processing of temporal information. Less