MANIPULATION OF SINGLE MACROMOLECULE AND DEVELOPMENT OF MOLECULAR ORGANIZATION

本研究项目旨在利用两亲性大单体设计和操纵两亲性组织聚合物。制备了带有苯乙烯或甲基丙烯酸酯端基的聚环氧乙烷（PEO）和其他水溶性高分子单体，并通过烷基间隔剂进行疏水增强。这些大单体在水中聚合非常迅速，形成具有疏水主干和亲水分支的规则梳状聚合物，并与疏水单体在水或酒精介质中共聚，形成亚微米到微米大小的可控聚合物微球。该项目揭示了这些两亲性高分子单体在水中胶束聚合的基本机理，揭示了规则密支梳状聚合物的构象特征，并为聚合物微球的设计提供了基本指导。此外，还制备了一种由导电主链和PEO接枝链组成的新型两亲性梳状聚合物。将本研究合成的梳状聚合物浇铸在云母上，进行原子力显微镜观察。我们成功地观察和操纵了一种聚合物。

This research project aimed at design and manipulation of amphiphilically organized polymers by taking advantage of amphiphilic macromonomers. Poly(ethylene oxide) (PEO) and other water soluble macromonomers carrying styryl or methacrylate end groups, hydrophobically enhanced by alkylene spacers, were prepared. These macromonomers were found to polymerize very rapidly in water to afford regular comb polymers with hydrophobic trunks and hydrophilic branches, and copolymerize with a hydrophobic monomer in water or alcoholic media to give controlled polymeric microspheres of submicron to micron size. This project has thus disclosed a basic mechanism of micellar polymerization of these amphiphilic macromonomers in water, conformational characterization of regularly and densely branched comb polymers, and a fundamental guideline to the polymeric microspheres' design. In addition, a new type amphiphilic comb polymers consisting of a conducting main chain and PEO grafted chains. The comb polymers synthesized in this study were cast onto a mica to carry out the atomic force microscopic observation. We succeeded in the observation and manipulation of a single polymer.