Treatment of dentin hypersensitivity and dental caries by ammonium hexafluorosilicate

在日本，临床上使用二胺氟化银来预防龋齿的发展。然而，由于硫化银的沉淀，二胺氟化银会使牙齿变黑。为了解决这一缺陷，我们制备了不染牙的六氟硅酸铵，发现六氟硅酸铵与酸化氟化磷酸（APF）和二胺氟化银相比，提高了磷灰石粉末的结晶度，形成了更多的氟化磷灰石。本研究的目的是评价六氟硅酸铵是否能提高牛牙釉质和牙本质的耐酸能力。牛牙釉质和牙本质器嵌入树脂，使唇侧暴露。将打磨后的牙齿表面用石蜡分成几部分，每一部分用氟化溶液（六氟硅酸铵、二胺氟化银、APF或NaF）处理3分钟，用蒸馏水洗净氟化溶液后，将牙齿浸入d . More矿化液中24小时。用表面粗糙度仪测量脱矿牙深度。同时，脱矿标本进行显微放射照相。六氟硅酸铵（81.6%）和二胺氟化银（83.7%）处理后的脱矿深度明显浅于对照{98.6^^+__- 40.0um(100%)}。APF或NaF治疗均未显著降低深度。在牙本质标本中，所有氟化物溶液都比对照组的深度降低。二胺氟化银（75.5%）和六氟硅酸铵（85.2%）处理比六氟硅酸铵处理后形成的层具有更强的耐酸性，而二胺氟化银处理阻止了脱矿的进展。结果表明，六氟硅酸铵在不改变牙体颜色的情况下，提高了牙釉质和牙本质的耐酸能力，对牙釉质和龋的防治有一定的作用。少

Diamine silver fluoride is clinically used to prevent progress of dental caries in Japan. However, diamaine silver fluoride stains teeth black due to silver sulfide precipitation. To solve this drawback, we prepared ammonium hexafluorosilicate which dose not stain teeth, and we found ammonium hexafluorosilicate increased crystallinity of apatite powder and formed lager amount of fluoridated apatite when compared with acidulated phosphate fluoride (APF) or diamine silver flioride. The aim of this study was to evaluate whether or not ammonium hexafluorosilicate increase acid resistance of bovine enamel and dentin. Bovaine enamel and dentin ware embedded into resin leaving labial side exposed. The polished surface was divided into several portions using paraffin wax and each portion was treated with a fluoride solution (ammonium hexafluorosilicate, diamine silver fluoride, APF or NaF) for 3 min. after the fluoride solutions were washed out with distilled water, the tooth was immersed in d … More emineralization solution for 24 hours. The depth of demineralized tooth was measured with surface roughness analyzer. Also, the demineralized specimens were subjected microradiography. In the enamel specimens, demineralized depth after treated with ammonium hexafluorosilicate (81.6%) or diamine silver fluoride (83.7%) was significantly shallower than that of control {98.6^^+__- 40.0um(100%)}. Treatment with APF or NaF did not reduce the depth significantly. All fluoride solutions reduced the depth than that of control in dentin specimens. Diamine silver fluoride (75.5%) and ammonium hexafluorosilicate (85.2%) treatments showed greater acid resistance than the layer formed after ammonium hexafluorosilicate od diamine silver fluoride treatment prevented progress of demineralization. We concluded that ammonium hexafluorosilicate is useful to prevent enamel and caries since ammonium hexafluorosilicate trearment increased acid resistance of enamel and dentin without changing the color of tooth. Less