The role of vestibular cortex in control of eye movements

长期以来，“前庭皮质”的存在一直备受争议。到目前为止，已经报道了不止一个区域接收前庭信息，但前庭输入到大脑皮层的详细特性尚未确定。这项研究是为了调查整个范围的皮质区接受前庭输入。猴子的中耳位于颈部表面的深处，这使得手术方法和电极设置非常困难。为了将刺激电极放置在前庭神经上，必须开发一种新的经中耳途径。采用上述方法，将银球电极置于内耳窗附近，刺激前庭神经。诱发电位记录从皮质表面的各个皮质区。其中2 v区和6pa区表现出明显的不确定性响应，并在这些区域进行了层流场分析。因此，可以得出结论， ...更多信息 r皮质和6pa区接受较强的前庭输入.在对猫和猴的丘脑刺激所引起的皮层反应进行层流场分析时，已报道有两种丘脑皮层反应：浅丘脑皮层反应和深丘脑皮层反应。我们以前的研究表明，浅和深丘脑皮层反应反映的轴突终末的丘脑皮层神经元在layeis I和II，和III-V层，分别。基于这些发现，本文对岛叶皮层和6pa区前庭诱发场电位的层场分析表明，前庭信息通过丘脑皮层浅层和深层投射传递到大脑皮层.必须排除这样的可能性，即我们观察到的诱发反应是电流传播到位于中耳的其他神经（听觉神经和面神经）的结果。通过切断内耳道中的每条神经，在上行MLF中制造损伤，排除了这些可能性。结果表明，上述前庭诱发反应均为前庭神经源性反应.这些结果已提交给《神经科学杂志》。少

The presence of the "vestibular cortex" has been very controversial for a long time. More than one areas have been reported to receive vestibular information so far, but the detailed properties of vestibular inputs to the cerebral cortex are yet to be determined. This study was performed to survey the whole extent of the cortical areas that receive vestibular inputs.1. The middle ear in the monkey is located deep from the neck surface, which makes surgical approach and electrode set-up very difficult. To place the stimulating electrodes on the vestibular nerves, a new trans-middle ear approach had to be developed.2. Using the above approach, silver ball electrodes were placed near the inner ear windows and the vestibular nerves were stimulated. Evoked potentials were recorded from the cortical surface of various cortical areas. Among them, areas 2v and 6pa showed 〓〓〓quivocal responses, and laminar field analysis was performed in these areas. As a result, it is concluded that the insula … More r cortex and area 6pa receive strong vestibular inputs.3. It has been reported from laminar field analysis of the cortical responses evoked by stimulation of the thalamus in the cat and monkey that there are two kinds of the thalamocortical responses; the superficial and deep thalamocortical response. Our previous study showed that superficial and deep thalamocortical responses reflect axon terminals of thalamocortical neurons in layeis I and II, and layers III-V, respectively. Based on these findings, the present laminar field analysis of the vestibular evoked field potentials recorded in the insular cortex and area 6pa revealed that the vestibular information is relayed to the cerebral cortex by both the superficial and the deep thalamocortical projection.4. It is essential to exclude the possibility that the evoked responses that we observed are the results of the current spread to other nerves located in the middle ear; the auditory nerve and the facial nerve. These possibilities were excluded by cutting each nerve in the internal auditory canal, 01 making lesion in the ascending MLF. The results showed that the above-mentioned vestibular evoked responses were of really vestibular nerve origin.5. These results were submitted to Journal of Neuroscience. Less