Measurement of Electrooculogram(EOG) Using an Improved Method and Quantitative Analysis of Cross Talk

本研究的目的是利用眼球电池模型分析眼电图（EOG）的特征，以提高临床诊断质量。本研究采用了改进的常规眼电测量方法。在传统的眼电测量方法中，采用双极电极法，测量内、外耳一个为负、一个为正的电位差。在本研究中，使用单极电极方法，检测来自每个电极的电位为正极性（负极性）对身体。应用上述方法，眼周个体眼电特征和串扰特征清晰。双侧正常眼的EOG电位已经包含了另一只眼的串扰。另一方面，对于单侧眼无症状的受试者，可以从健康眼测量真实眼电信号，并从眼无症状一侧获得净串音电位，因此这类受试者有助于串音特征的分析。对几例单侧无眼症患者的眼电信号进行了连续测量。无眼侧内眼角的平均串音值为正常眼侧内眼角电位的25%，无眼侧外眼角的平均串音值为11%。应用眼球电池模型对单侧眼失症患者的眼电测量数据进行分析。在之前的文章中提出了串扰抵消的理论概念，在正常受试者双眼健康的情况下，将串扰值代入推导出的方程，即可实现串扰抵消。

The purpose of this research is to analyze the characteristics of electrooculogram (EOG) applying a battery model of the eyeball to enhance the quality of clinical diagnosis more than ever. The improved method for the conventional EOG measurement was used in this research. In the conventional method of EOG measurement, the bipolar electrode method, measuring the potential difference between the inner and outer canthi as one is negative and another positive, was used. In this research, the monopolar electrode method, detecting the potentials from every electrode as positive polarity against the body (minus), was used. Applying the above methods, the individual EOG characteristics around the eye and the features of the cross-talk became clear. The EOG potentials obtained from the subjects with bilaterally normal eyes already contain the cross-talk from another eye. On the other hand, in the subjects with unilateral anophthalmia, the real EOG can be measured from the healthy eye and the net cross-talk potential can be gotten from the anophthalmia side, therefore such subjects are helpful for analysis of cross-talk characteristics.The EOG data from several subjects with unilateral anophthalmia were measured continuously in current year. The mean cross-talk value to the inner canthus on anophthalmia side was 25% of the potential at the inner canthus on the normal eye side, and the mean cross-talk value to the outer canthus on the anophthalmia side was 11%. The EOG characteristics in various cases were analyzed by applying a battery model of eyeball to the measured EOG data from the subjects with unilateral anophthalmia. As the theoretical concept of the cross-talk cancellation is proposed previous paper, the cross-talk can be able to cancel in case of the normal subjects with both healthy eyes by substituting the cross-talk values to the derived equation.