Study on production domestic animals biosynthesized conjugated fatty acids that carries anti-obesity effects

据报道，共轭亚油酸对癌症和肥胖症有效。在这项研究中，共轭亚油酸异构酶（PAISOM）的基因被引入到牛细胞。我们获得了稳定转染PAISOM基因的细胞。我们还成功地从PAISM细胞中产生了克隆胚胎。然而，PAISM-细胞中脂肪酸的气相色谱法未显示共轭亚油酸，但我们检测到未知但可能是共轭花生四烯酸的峰，其从共轭亚油酸延长。

Conjugated linoleic acid has been reported to be effective for cancers and obesity. In this study, a gene for an isomerase for conjugated linoleic acid (PAISOM) was introduced into bovine cells. We obtained cells stably transfected with PAISOM gene. We also successfully produced cloned embryos from the PAISOM-cells. However, Gas chromatography of fatty acids in the PAISOM-cells did not indicate the conjugated linoleic acid, but we detected a peak unknown but likely to be conjugated arachidonic acid that were elongated from conjugated linoleic acid.