Fabrication of chiral recognition by stimuli-responsive coacervate

我们新设计了基于异丙基丙烯酰胺(IPAAm)的随机含羧基或羟基的共聚物。研究了它们对共聚单体组成、盐浓度和溶液pH的温度响应行为。此外，我们还通过有效的交联反应研究了凝聚液滴的形成和相应的微米级水凝胶。使用两种不同官能团的IPAAm基共聚物，得到的凝聚体为完全熔融型，水凝胶呈现半互穿聚合物网络结构。此外，所得到的水凝胶具有非常敏感的温度和pH响应特性。

We newly designed isopropylacrylamide(IPAAm)-based copolymers randomly containing carboxyl or hydroxyl groups. Their temperature-responsive behavior on comonomer composition, salt concentration and pH of the solution was precisely investigated. Furthermore, we studied coacervate droplet formation and corresponding micrometer-sized hydrogel by effective cross-linking reaction. Using the two kinds of IPAAm-based copolymer with different functional moieties, the obtained coacervate was completely fusion-type and the hydrogel showed semi-interpenetrating polymer network structure. Furthermore, the obtained hydrogel showed very sensitive temperature-and pH-responsive properties.