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Analysis of function and regulatory mechanism of mRNA expression of bird specific transcription factor in the anterior pituitary gland

Analysis of function and regulatory mechanism of mRNA expression of bird specific transcription factor in the anterior pituitary gland
鸟类垂体前叶特异性转录因子mRNA表达的功能及调控机制分析
批准号:
19580330
负责人:
KANSAKU Norio
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009

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项目成果

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中文摘要
翻译
克隆了Pit-1基因的早熟和早熟鸟类内含子1,并进行了序列测定。Pit-1w/γ推测的翻译起始点在其他物种中的同源位置不是蛋氨酸密码子。由此可见,Pit-1w/γ基因在野生种中不存在。此外,还利用RT-PCR技术克隆了转录起始区。本研究结果表明,Pit-1w/γ的调控区域比之前预期的要小。
英文摘要
Intron 1 of the precocial and altricial bird of the Pit-1 gene were cloned and sequenced. Homologous position of putative translation starting site of Pit-1w/γ in the altricial species was not ATG methionin codon. Thus, it is suggested that Pit-1w/γ is not exist in the altricial species. Moreover, transcription starting region was cloned by RT-PCR. Results of this study showed that regulatory region of Pit-1w/γ is smaller than previously expected.
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DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [N. Kansaku, T. Sasanami, T. Ohkubo, G. Hiyama, D. Zadworny]
通讯作者: D. Zadworny
DOI: 10.1111/j.1740-0929.2008.00513.x
发表时间: 2008-04
期刊: Animal Science Journal
影响因子: 2
作者: [N. Kansaku;A. Soma;S. Furukawa;Gen Hiyama;Hisato Okabayashii;D. Guemene;U. Kuhnlein;D. Zadworny]
通讯作者: N. Kansaku;A. Soma;S. Furukawa;Gen Hiyama;Hisato Okabayashii;D. Guemene;U. Kuhnlein;D. Zadworny
Sequence comparison of the prolactin (PRL) promoter in BUT and Bettina turkeys
BUT 和 Bettina 火鸡催乳素 (PRL) 启动子的序列比较
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [Hiyama, G., Kansaku, N., Reddy, I.J., Sotocinal, S., Guemene, D., Zadworny, D.]
通讯作者: D.
Prolactin and growth hormone in bird: protein structure, gene structure, and genetic variation.
鸟类催乳素和生长激素:蛋白质结构、基因结构和遗传变异。
DOI: --
发表时间: 2008
期刊: Journal of Poultry Science 45
影响因子: --
作者: [Kansaku, N., Hiyama, G., Sasanami, T., Zadworny.]
通讯作者: Zadworny.
共 11 条
    Regulatory mechanism of hormone gene expression in the anterior pituitary gland in birds
    • 批准号:
      22580322
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.83万
    • 财政年份:
      2010
    • 负责人:
      KANSAKU Norio
    • 依托单位:
    海外基金