Randomized controlled trial of calcium supplementation

本研究的目的是揭示补钙对绝经后妇女骨质流失的可能影响。450名妇女被分为以下三组：1)接受500毫克/天的钙补充剂，2)接受250毫克/天的钙补充剂，3)安慰剂。比较三组患者股骨颈和腰椎2年骨密度损失情况。两组补钙组腰椎骨质流失明显小于安慰剂组。每日补钙250毫克可预防日本女性脊柱骨质流失。

The aim of this study was to reveal a possible effect of calcium supplementation on bone loss of postmenopausal women. Four-hundred fifty women were divided into the following three groups : 1) receiving 500 mg/day of calcium supplement, 2) receiving 250 mg/day of calcium supplement, and 3) placebo. Loss of bone mineral density in femoral neck and lumbar spine for two years was compared among the three groups. Bone loss of lumbar spine in the two calcium supplement groups was significantly smaller than the placebo group. A calcium supplement 250 mg/day prevents spinal bone loss of Japanese women.