Studies on the ecology of Bartonella species by molecular biological approach

我们调查了巴尔通体在野生和进口啮齿动物中的流行情况。我们还检测了从啮齿动物和无家可归的人收集的外寄生虫巴尔通体的基因。在685只啮齿动物中，我们成功地从176只中分离出巴尔通体（分离率为25.7%）。分离的巴尔通体均来自郊区捕获的鼠类，分离率为51.8%。在2007-2008年期间，33.3%的体虱和25%的头虱感染的无家可归者在美国有B的DNA。quintana。此外，序列分析表明，在泰国的33个恙螨池和一个蜱池中检测到的DNA与B相似。tamiae序列先前从该国的三名患者中分离出来。spp.in546只（28种）进口小型哺乳动物进行了巴尔通体的流行病学调查。共分离巴尔通体407株，检出人畜共患巴尔通体4株，新发现巴尔通体6株。

We investigated the prevalence of Bartonella species in wild and imported rodents. We also detected the genes of Bartonella in ectoparasite collected from rodents and homeless peoples. We successfully isolated Bartonella organisms from 176 of the 685 rodents (isolation rate, 25.7%). Those Bartonella isolates were all obtained from the rodents captured in suburban areas (rate, 51.8%). During 2007-2008, 33.3% of body lice- and 25% of head lice-infested homeless peoples in USA had DNA of B. quintana. Furthermore, sequence analysis demonstrated that DNA detected in 33 chigger mite pools and one tick pool from wild rodents in Thailand was similar to B. tamiae sequences previously isolated from three patients in the country. We investigated the prevalence of Bartonella spp.in 546 imported small mammals (28 species). We obtained 407 Bartonella isolates and the animals examined were found to harbor 4 zoonotic Bartonella spp.and 6 novel Bartonella spp..