Physical exercise enhanced the sensory function in the knee joint with aging and disuse

本研究的目的是分析运动是否能增强随年龄增长和废用的膝关节的神经功能。运动大鼠表现出神经营养因子免疫染色的定量增加，这在脊髓中最为明显。生化检测表明，运动选择性地增加了衰老脊髓中神经营养因子及其受体mRNA的表达。这些结果表明，运动通过生理过程增强了支配膝关节的腰髓中的神经营养素及其受体。

The purpose of study is to analyze whether physical exercise enhanced the neural function in the knee joint with aging and disuse. Exercised rats showed a quantitative increase neurotrophin immunostaining that was mostly evident in the spinal cords. In biochemical assay, exercise increases selectively expression of neurotrophins and receptors mRNA in the lumber spinal cord in senescence. These results suggest that exercise enhanced neurotrophins and their receptors by physiological process that it is endogenous in the lumber spinal cords which innervate the knee joints.