Development of small-diameter vascular graft composed of antithrombogenic phospholipid polymer
Development of small-diameter vascular graft composed of antithrombogenic phospholipid polymer
批准号:
21591628
负责人:
OKAMOTO Hiroyuki
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
经mpc包被和未包被ePTFE移植的颈动脉或股动脉绕道1周后的通畅率分别为9/37(24%)和14/37(38%);2周后为4/37(11%)和6/37(15%);4周后为3/37(8%)和3/37(8%)。根据组织学检查,血栓附着在宿主动脉的切边上。与未包被的移植物相比,包被的移植物吻合口和表面的内膜增生无明显变化。
英文摘要
The patency rates of carotid or femoral arterial bypass with MPC-coated and noncoated ePTFE grafts were 9/37(24%) and 14/37(38%) after one week ; 4/37(11%) and 6/37(15%) after two weeks ; and 3/37(8%) and 3/37(8%) after four weeks. Based on a histological examination, the thrombus was attached to the cut edges of the host artery. Intimal hyperplasia at the anastomosis and the surface of MPC-coated grafts was not changed remarkably compared with noncoated grafts.
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